ENSDARG00000037870


Danio rerio

Features
Gene ID: ENSDARG00000037870
  
Biological name :actb2
  
Synonyms : actb2 / actin, beta 2 / Q7ZVF9
  
Possible biological names infered from orthology : ACTB / ACTG1 / actin beta / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / Actin, cytoplasmic 2 Actin, cytoplasmic 2, N-terminally processed / actin gamma 1 / P0CG39 / P60709 / P60710 / P63260 / P63261 / POTE ankyrin domain family member J / POTEJ
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 40526107
Gene end: 40529804
  
Corresponding Affymetrix probe sets: Dr.1109.1.S1_at (Zebrafish Array)   NM_181601_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000122263
Ensembl peptide - ENSDARP00000147775
Ensembl peptide - ENSDARP00000055193
Ensembl peptide - ENSDARP00000120388
NCBI entrez gene - 57935     See in Manteia.
RefSeq - NM_181601
RefSeq Peptide - NP_853632
swissprot - A8WG05
swissprot - F1QC15
swissprot - Q7ZVF9
ZFIN ID - ZDB-GENE-000329-3
Ensembl - ENSDARG00000037870
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACTBENSGALG00000009621Gallus gallus
 ACTC2LENSGALG00000028749Gallus gallus
 ACTG1ENSGALG00000001381Gallus gallus
 ACTBENSG00000075624Homo sapiens
 ACTG1ENSG00000184009Homo sapiens
 POTEJENSG00000222038Homo sapiens
 ActbENSMUSG00000029580Mus musculus
 Actg1ENSMUSG00000062825Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
actb1 / Q7ZVI7 / actin, beta 1 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...ENSDARG00000037746100
acta2 / actin, alpha 2, smooth muscle, aorta / P62736* / P62737* / Actin, aortic smooth muscle Actin, aortic smooth muscle, intermediate form*ENSDARG0000004518094
ACTC1 / zgc:86709 / P68032* / P68033* / actin, alpha, cardiac muscle 1*ENSDARG0000005791194
actc1a / actin, alpha, cardiac muscle 1a / ACTC1* / P68032* / P68033* / actin, alpha, cardiac muscle 1*ENSDARG0000004253594
actc1a / actin, alpha, cardiac muscle 1a / ACTC1* / P68032* / P68033* / actin, alpha, cardiac muscle 1*ENSDARG0000007612694
acta1a / actin, alpha 1a, skeletal muscleENSDARG0000003637194
acta1b / actin, alpha 1b, skeletal muscleENSDARG0000005561893
acta2 / actc1b / actin, alpha, cardiac muscle 1b / ACTC1* / P68032* / actin, alpha, cardiac muscle 1*ENSDARG0000009919793
actc1c / actin, alpha, cardiac muscle 1c / ACTG2* / P63268* / P63267* / Actin, gamma-enteric smooth muscle * / actin, gamma 2, smooth muscle, enteric*ENSDARG0000007911192
actr1 / ARP1 actin related protein 1, centractin / Q8R5C5* / ACTR1B* / P42025* / Beta-centractin * / ARP1 actin related protein 1 homolog B*ENSDARG0000001161154
si:ch211-241j12.3ENSDARG0000004396351


Protein motifs (from Interpro)
Interpro ID Name
 IPR004000  Actin family
 IPR004001  Actin, conserved site
 IPR020902  Actin/actin-like conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton ISS
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005925 focal adhesion ISS
 cellular_componentGO:0097433 dense body ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Gap junction degradation
Formation of annular gap junctions
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
Adherens junctions interactions
Recycling pathway of L1
VEGFA-VEGFR2 Pathway
Interaction between L1 and Ankyrins
Cell-extracellular matrix interactions
RHO GTPases activate IQGAPs
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate Formins
MAP2K and MAPK activation
UCH proteinases
DNA Damage Recognition in GG-NER
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007723 efnb1 / ephrin-B1 / P52795* / P98172*  / complex / reaction
 ENSDARG00000018328 rhocb / Q6DHE8 / ras homolog family member Cb / RHOC* / Q62159* / P08134* / ras homolog family member C* / Rho-related GTP-binding protein RhoC *  / reaction / complex
 ENSDARG00000094673 rhoab / Q6DHM9 / ras homolog gene family, member Ab / RHOA* / Q9QUI0* / P61586* / ras homolog family member A*  / complex / reaction
 ENSDARG00000035650 evla / Enah/Vasp-like a / EVL* / Q9UI08* / P70429* / Enah/Vasp-like* / Ena/VASP-like protein *  / complex / reaction
 ENSDARG00000021539 ephb2b / eph receptor B2b / EPHB2* / P29323* / P54763* / EPH receptor B2* / Ephrin type-B receptor 2 *  / complex / reaction
 ENSDARG00000020164 efnb2a / O73874 / ephrin-B2a / EFNB2* / P52799* / P52800* / ephrin B2*  / complex / reaction
 ENSDARG00000037746 actb1 / Q7ZVI7 / actin, beta 1 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / - / reaction / complex
 ENSDARG00000042277 efnb3b / ephrin-B3b / EFNB3* / Q15768* / ephrin B3*  / complex / reaction
 ENSDARG00000018566 flnca / filamin C, gamma a (actin binding protein 280) / FLNC* / Q14315* / Q8VHX6* / filamin C*  / complex / reaction
 ENSDARG00000037870 actb2 / Q7ZVF9 / actin, beta 2 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / reaction / complex / -
 ENSDARG00000017004 myo10 / myosin X / F8VQB6* / Q9HD67* / Mus musculus myosin X (Myo10), transcript variant 3, mRNA.*  / complex / reaction
 ENSDARG00000041065 hspb1 / heat shock protein, alpha-crystallin-related, 1 / P14602* / P04792* / Heat shock protein beta-1 * / heat shock protein family B (small) member 1*  / complex
 ENSDARG00000018820 flncb / filamin C, gamma b (actin binding protein 280) / FLNC* / Q14315* / filamin C*  / complex / reaction
 ENSDARG00000060010 iqgap2 / IQ motif containing GTPase activating protein 2 / Q13576* / Q3UQ44* / Ras GTPase-activating-like protein IQGAP2 *  / reaction / complex
 ENSDARG00000032161 B0S6J3 / srgap2 / SLIT-ROBO Rho GTPase activating protein 2 / O75044* / Q91Z67* / P0DJJ0* / P0DMP2* / SRGAP2C* / SRGAP2B* / SLIT-ROBO Rho GTPase activating protein 2B* / SLIT-ROBO Rho GTPas...  / reaction / complex
 ENSDARG00000044573 cdc42 / cell division cycle 42 / P60766* / P60953* / Cell division control *  / complex / reaction
 ENSDARG00000019231 sptan1 / spectrin alpha, non-erythrocytic 1 / SPTA1* / Q13813* / P08032* / P16546* / P02549* / spectrin alpha, erythrocytic 1* / Spectrin alpha chain, erythrocytic 1 * / Spectrin alpha chai...  / complex
 ENSDARG00000021309 rhoca / ras homolog family member Ca / RHOC* / Q62159* / P08134* / ras homolog family member C* / Rho-related GTP-binding protein RhoC *  / reaction / complex
 ENSDARG00000074050 efnb2b / ephrin-B2b / EFNB2* / P52800* / P52799* / ephrin B2*  / complex / reaction
 ENSDARG00000004372 fmnl3 / Q6NXC0 / formin-like 3 / Q8IVF7* / Q6ZPF4* / Formin-like protein 3 *  / complex / reaction
 ENSDARG00000076757 ephb1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *  / reaction / complex
 ENSDARG00000112993 efnb3a / ephrin-B3a / EFNB3* / Q15768* / O35393* / ephrin B3*  / complex / reaction
 ENSDARG00000055713 fmnl1a / formin-like 1a / FMNL1* / O95466* / Q9JL26* / formin like 1* / Formin-like protein 1 *  / complex
 ENSDARG00000037373 ephb2a / eph receptor B2a / EPHB2* / P29323* / P54763* / EPH receptor B2* / Ephrin type-B receptor 2 *  / complex / reaction






 

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