ENSDARG00000035650


Danio rerio

Features
Gene ID: ENSDARG00000035650
  
Biological name :evla
  
Synonyms : Enah/Vasp-like a / evla
  
Possible biological names infered from orthology : Enah/Vasp-like / Ena/VASP-like protein / EVL / P70429 / Q9UI08
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 30897292
Gene end: 30975978
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000121600
Ensembl peptide - ENSDARP00000146002
Ensembl peptide - ENSDARP00000051696
NCBI entrez gene - 58003     See in Manteia.
RefSeq - NM_199519
RefSeq Peptide - NP_955813
swissprot - E9QFB8
swissprot - Q7SZN7
ZFIN ID - ZDB-GENE-000607-65
Ensembl - ENSDARG00000035650
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EVLENSGALG00000011209Gallus gallus
 EVLENSG00000196405Homo sapiens
 EvlENSMUSG00000021262Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
evlb / Enah/Vasp-like bENSDARG0000009972062
enah / enabled homolog (Drosophila) / Q03173* / Q8N8S7* / ENAH, actin regulator*ENSDARG0000003204951
vaspb / vasodilator stimulated phosphoprotein b / VASP* / P50552* / P70460* / vasodilator stimulated phosphoprotein*ENSDARG0000001710549
vaspa / vasodilator stimulated phosphoprotein a / VASP* / P50552* / vasodilator stimulated phosphoprotein*ENSDARG0000009969043
spred2a / sprouty-related, EVH1 domain containing 2a / Q924S7* / SPRED2* / Q7Z698* / sprouty related EVH1 domain containing 2* / Sprouty-related, EVH1 domain-containing protein 2 *ENSDARG0000005243518
spred1 / sprouty-related, EVH1 domain containing 1 / Q7Z699* / Q924S8* / Sprouty-related, EVH1 domain-containing protein 1 *ENSDARG0000004144917
spred2b / sprouty-related, EVH1 domain containing 2b / Q924S7* / SPRED2* / Q7Z698* / sprouty related EVH1 domain containing 2* / Sprouty-related, EVH1 domain-containing protein 2 *ENSDARG0000000837216
spred3 / sprouty-related, EVH1 domain containing 3 / Q2MJR0*ENSDARG0000004035815


Protein motifs (from Interpro)
Interpro ID Name
 IPR000697  WH1/EVH1 domain
 IPR011993  PH-like domain superfamily
 IPR014885  VASP tetramerisation
 IPR017354  Vasodilator-stimulated phosphoprotein/ENA/VASP-like
 IPR034319  ENA/VASP-like protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008154 actin polymerization or depolymerization IEA
 biological_processGO:0051289 protein homotetramerization IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0017124 SH3 domain binding IEA


Pathways (from Reactome)
Pathway description
Signaling by ROBO receptors
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000004246 slit2 / slit homolog 2 (Drosophila) / O94813* / Q9R1B9* / slit guidance ligand 2*  / complex
 ENSDARG00000035650 evla / Enah/Vasp-like a / EVL* / Q9UI08* / P70429* / Enah/Vasp-like* / Ena/VASP-like protein *  / complex
 ENSDARG00000094673 rhoab / Q6DHM9 / ras homolog gene family, member Ab / RHOA* / Q9QUI0* / P61586* / ras homolog family member A*  / complex / reaction
 ENSDARG00000037746 actb1 / Q7ZVI7 / actin, beta 1 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / complex / reaction
 ENSDARG00000037870 actb2 / Q7ZVF9 / actin, beta 2 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / complex / reaction






 

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