ENSDARG00000052435


Danio rerio

Features
Gene ID: ENSDARG00000052435
  
Biological name :spred2a
  
Synonyms : spred2a / sprouty-related, EVH1 domain containing 2a
  
Possible biological names infered from orthology : Q7Z698 / Q924S7 / SPRED2 / sprouty related EVH1 domain containing 2 / Sprouty-related, EVH1 domain-containing protein 2
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 51444549
Gene end: 51474974
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000068773
Ensembl peptide - ENSDARP00000126773
swissprot - E7F0P6
swissprot - R4GE60
ZFIN ID - ZDB-GENE-110830-2
Ensembl - ENSDARG00000052435
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPRED2ENSGALG00000008778Gallus gallus
 Q7Z698ENSG00000198369Homo sapiens
 Q924S7ENSMUSG00000045671Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
spred2b / sprouty-related, EVH1 domain containing 2b / Q924S7* / SPRED2* / Q7Z698* / sprouty related EVH1 domain containing 2* / Sprouty-related, EVH1 domain-containing protein 2 *ENSDARG0000000837271
spred1 / sprouty-related, EVH1 domain containing 1 / Q7Z699* / Q924S8* / Sprouty-related, EVH1 domain-containing protein 1 *ENSDARG0000004144946
spred3 / sprouty-related, EVH1 domain containing 3 / Q2MJR0*ENSDARG0000004035838
enah / enabled homolog (Drosophila) / Q03173* / Q8N8S7* / ENAH, actin regulator*ENSDARG0000003204919
evla / Enah/Vasp-like a / EVL* / Q9UI08* / P70429* / Enah/Vasp-like* / Ena/VASP-like protein *ENSDARG0000003565016
vaspb / vasodilator stimulated phosphoprotein b / VASP* / P50552* / P70460* / vasodilator stimulated phosphoprotein*ENSDARG0000001710516
evlb / Enah/Vasp-like bENSDARG0000009972015
vaspa / vasodilator stimulated phosphoprotein a / VASP* / P50552* / vasodilator stimulated phosphoprotein*ENSDARG0000009969014


Protein motifs (from Interpro)
Interpro ID Name
 IPR000697  WH1/EVH1 domain
 IPR007875  Sprouty
 IPR011993  PH-like domain superfamily
 IPR023337  c-Kit-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 cellular_componentGO:0016020 membrane IEA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs
FGFRL1 modulation of FGFR1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052435 spred2a / sprouty-related, EVH1 domain containing 2a / Q924S7* / SPRED2* / Q7Z698* / sprouty related EVH1 domain containing 2* / Sprouty-related, EVH1 domain-containing protein 2 *  / complex
 ENSDARG00000032617 fgfrl1a / fibroblast growth factor receptor like 1a / Q91V87* / FGFRL1* / Q8N441* / fibroblast growth factor receptor like 1*  / complex / reaction






 

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