ENSDARG00000032617


Danio rerio

Features
Gene ID: ENSDARG00000032617
  
Biological name :fgfrl1a
  
Synonyms : fgfrl1a / fibroblast growth factor receptor like 1a
  
Possible biological names infered from orthology : FGFRL1 / fibroblast growth factor receptor like 1 / Q8N441 / Q91V87
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 17442913
Gene end: 17563773
  
Corresponding Affymetrix probe sets: Dr.26455.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000077102
NCBI entrez gene - 393347     See in Manteia.
swissprot - Q7SX76
ZFIN ID - ZDB-GENE-040128-2
Ensembl - ENSDARG00000032617
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FGFRL1ENSGALG00000037525Gallus gallus
 FGFRL1ENSG00000127418Homo sapiens
 Fgfrl1ENSMUSG00000008090Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fgfrl1b / fibroblast growth factor receptor like 1bENSDARG0000005255655
fgfr1bl / fibroblast growth factor receptor 1b, likeENSDARG0000010401520


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0021592 fourth ventricle development IMP
 biological_processGO:0021670 lateral ventricle development IMP
 biological_processGO:0021678 third ventricle development IMP
 biological_processGO:0048565 digestive tract development IMP
 biological_processGO:0048592 eye morphogenesis IMP
 biological_processGO:0048794 swim bladder development IMP
 biological_processGO:0051216 cartilage development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
FGFRL1 modulation of FGFR1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder decreased size , abnormal
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 ZFA:0000107 eye eye morphology , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage shape , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton morphology , abnormal
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 ZFA:0001261 ventricular system ventricular system distended , abnormal
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 ZFA:0001276 pharyngeal arch 2 skeleton pharyngeal arch 2 skeleton shape , abnormal
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 ZFA:0001338 intestine intestine hypoplastic , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage shape , abnormal
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 ZFA:0001461 chondrocranium cartilage chondrocranium cartilage decreased size , abnormal
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 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage aplastic , abnormal
ceratobranchial cartilage decreased size , abnormal
ceratobranchial cartilage decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000032617 fgfrl1a / fibroblast growth factor receptor like 1a / Q91V87* / FGFRL1* / Q8N441* / fibroblast growth factor receptor like 1*  / complex
 ENSDARG00000076510 fgf22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*  / complex / reaction
 ENSDARG00000100475 fgf10b / fibroblast growth factor 10b / FGF10* / O15520* / fibroblast growth factor 10*  / complex / reaction
 ENSDARG00000030932 fgf10a / fibroblast growth factor 10a / FGF10* / O35565* / O15520* / fibroblast growth factor 10*  / complex / reaction
 ENSDARG00000052435 spred2a / sprouty-related, EVH1 domain containing 2a / Q924S7* / SPRED2* / Q7Z698* / sprouty related EVH1 domain containing 2* / Sprouty-related, EVH1 domain-containing protein 2 *  / reaction / complex
 ENSDARG00000101540 fgf3 / P48802 / fibroblast growth factor 3 / P11487*  / complex / reaction
 ENSDARG00000105230 fgf4 / fibroblast growth factor 4 / P08620* / P11403*  / complex / reaction






 

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