ENSDARG00000041449


Danio rerio

Features
Gene ID: ENSDARG00000041449
  
Biological name :spred1
  
Synonyms : spred1 / sprouty-related, EVH1 domain containing 1
  
Possible biological names infered from orthology : Q7Z699 / Q924S8 / Sprouty-related, EVH1 domain-containing protein 1
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 52639492
Gene end: 52659119
  
Corresponding Affymetrix probe sets: Dr.10038.1.S1_at (Zebrafish Array)   Dr.23460.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000060763
Ensembl peptide - ENSDARP00000147699
swissprot - F1R8L9
ZFIN ID - ZDB-GENE-040426-2338
Ensembl - ENSDARG00000041449
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPRED1ENSGALG00000028203Gallus gallus
 Q7Z699ENSG00000166068Homo sapiens
 Q924S8ENSMUSG00000027351Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
spred2b / sprouty-related, EVH1 domain containing 2b / Q924S7* / SPRED2* / Q7Z698* / sprouty related EVH1 domain containing 2* / Sprouty-related, EVH1 domain-containing protein 2 *ENSDARG0000000837252
spred2a / sprouty-related, EVH1 domain containing 2a / Q924S7* / SPRED2* / Q7Z698* / sprouty related EVH1 domain containing 2* / Sprouty-related, EVH1 domain-containing protein 2 *ENSDARG0000005243550
spred3 / sprouty-related, EVH1 domain containing 3 / Q2MJR0*ENSDARG0000004035841
enah / enabled homolog (Drosophila) / Q03173* / Q8N8S7* / ENAH, actin regulator*ENSDARG0000003204918
evla / Enah/Vasp-like a / EVL* / Q9UI08* / P70429* / Enah/Vasp-like* / Ena/VASP-like protein *ENSDARG0000003565017
vaspa / vasodilator stimulated phosphoprotein a / VASP* / P50552* / vasodilator stimulated phosphoprotein*ENSDARG0000009969016
vaspb / vasodilator stimulated phosphoprotein b / VASP* / P50552* / P70460* / vasodilator stimulated phosphoprotein*ENSDARG0000001710516
evlb / Enah/Vasp-like bENSDARG0000009972015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000697  WH1/EVH1 domain
 IPR007875  Sprouty
 IPR011993  PH-like domain superfamily
 IPR023337  c-Kit-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway IMP
 biological_processGO:0048514 blood vessel morphogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs
FGFRL1 modulation of FGFR1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0001267 cranial vasculature cranial vasculature broken , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr