ENSGALG00000008778


Gallus gallus

Features
Gene ID: ENSGALG00000008778
  
Biological name :SPRED2
  
Synonyms : SPRED2 / sprouty related EVH1 domain containing 2
  
Possible biological names infered from orthology : Q7Z698 / Q924S7 / Sprouty-related, EVH1 domain-containing protein 2
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 10058485
Gene end: 10107666
  
Corresponding Affymetrix probe sets: Gga.11607.1.S1_at (Chicken Array)   Gga.14397.1.S1_s_at (Chicken Array)   Gga.19366.1.S1_s_at (Chicken Array)   GgaAffx.22685.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054610
Ensembl peptide - ENSGALP00000014259
NCBI entrez gene - 421271     See in Manteia.
RefSeq - XM_419341
RefSeq - XM_015278089
swissprot - F1NRN5
swissprot - A0A1D5PP14
Ensembl - ENSGALG00000008778
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spred2aENSDARG00000052435Danio rerio
 spred2bENSDARG00000008372Danio rerio
 Q7Z698ENSG00000198369Homo sapiens
 Q924S7ENSMUSG00000045671Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPRED1 / sprouty related EVH1 domain containing 1 / Q7Z699* / Q924S8* / Sprouty-related, EVH1 domain-containing protein 1 *ENSGALG0000002820356
ENAH / ENAH, actin regulator / Q03173* / Q8N8S7*ENSGALG0000000930318
EVL / ena/VASP-like protein / P70429* / Q9UI08* / Enah/Vasp-like*ENSGALG0000001120915


Protein motifs (from Interpro)
Interpro ID Name
 IPR000697  WH1/EVH1 domain
 IPR007875  Sprouty
 IPR011993  PH-like domain superfamily
 IPR023337  c-Kit-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0010801 negative regulation of peptidyl-threonine phosphorylation IEA
 biological_processGO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator IEA
 biological_processGO:0090311 regulation of protein deacetylation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005173 stem cell factor receptor binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030291 protein serine/threonine kinase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs
FGFRL1 modulation of FGFR1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008778 SPRED2 / sprouty related EVH1 domain containing 2 / Q7Z698* / Q924S7* / Sprouty-related, EVH1 domain-containing protein 2 *  / complex






 

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