ENSDARG00000041065


Danio rerio

Features
Gene ID: ENSDARG00000041065
  
Biological name :hspb1
  
Synonyms : heat shock protein, alpha-crystallin-related, 1 / hspb1
  
Possible biological names infered from orthology : Heat shock protein beta-1 / heat shock protein family B (small) member 1 / P04792 / P14602
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 3568016
Gene end: 3584815
  
Corresponding Affymetrix probe sets: Dr.12378.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000060161
Ensembl peptide - ENSDARP00000126452
NCBI entrez gene - 368243     See in Manteia.
swissprot - A4VAK4
swissprot - K7DYC3
ZFIN ID - ZDB-GENE-030326-4
Ensembl - ENSDARG00000041065
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSPB1ENSGALG00000001926Gallus gallus
 HSPB1ENSG00000106211Homo sapiens
 Hspb1ENSMUSG00000004951Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:dkey-1k23.3ENSDARG0000010542240
hspb15 / heat shock protein, alpha-crystallin-related, b15ENSDARG0000007841133
hspb8 / heat shock protein b8 / Q9UJY1* / Q9JK92* / Heat shock protein beta-8 * / heat shock protein family B (small) member 8*ENSDARG0000005836533
cryaba / crystallin, alpha B, aENSDARG0000004262131
cryaa / crystallin, alpha A / P02489* / CRYAA2* / P24622* / crystallin alpha A2* / Alpha-crystallin A chain *ENSDARG0000005350231
cryabb / crystallin, alpha B, b / CRYAB* / P23927* / P02511* / crystallin alpha B* / Alpha-crystallin B chain *ENSDARG0000010138030
hspb2 / heat shock protein, alpha-crystallin-related, b2 / Q16082* / Q99PR8* / HSPB2-C11orf52* / Heat shock protein beta-2 * / HSPB2-C11orf52 readthrough (NMD candidate)* / heat shock prote...ENSDARG0000005245028
hspb6 / heat shock protein, alpha-crystallin-related, b6 / O14558* / heat shock protein family B (small) member 6*ENSDARG0000007723621
hspb3 / heat shock protein, alpha-crystallin-related, b3 / Q9QZ57* / Q12988* / Heat shock protein beta-3 * / heat shock protein family B (small) member 3*ENSDARG0000006771420


Protein motifs (from Interpro)
Interpro ID Name
 IPR001436  Alpha crystallin/Heat shock protein
 IPR002068  Alpha crystallin/Hsp20 domain
 IPR008978  HSP20-like chaperone
 IPR031107  Small heat shock protein HSP20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009408 response to heat IDA
 biological_processGO:0014881 regulation of myofibril size IMP
 biological_processGO:0046685 response to arsenic-containing substance IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA


Pathways (from Reactome)
Pathway description
VEGFA-VEGFR2 Pathway
AUF1 (hnRNP D0) binds and destabilizes mRNA
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000301 medial rectus medial rectus decreased thickness , abnormal
Show

 ZFA:0007049 adductor mandibulae adductor mandibulae decreased thickness , abnormal
adductor mandibulae regulation of myofibril size disrupted , abnormal
adductor mandibulae muscle cell decreased size , abnormal
Show

 ZFA:0007051 interhyoideus interhyoideus decreased thickness , abnormal
interhyoideus regulation of myofibril size disrupted , abnormal
interhyoideus muscle cell decreased size , abnormal
Show

 ZFA:0009063 peripheral neuron peripheral neuron axon guidance process quality , abnormal
peripheral neuron axon morphology , abnormal
peripheral neuron axon shape , abnormal
peripheral neuron axon absent , abnormal
peripheral neuron axon branchiness , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037746 actb1 / Q7ZVI7 / actin, beta 1 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / complex
 ENSDARG00000037870 actb2 / Q7ZVF9 / actin, beta 2 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / complex
 ENSDARG00000041065 hspb1 / heat shock protein, alpha-crystallin-related, 1 / P14602* / P04792* / Heat shock protein beta-1 * / heat shock protein family B (small) member 1*  / -
 ENSDARG00000028082 mapkapk5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41*  / reaction






 

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