ENSDARG00000101380


Danio rerio

Features
Gene ID: ENSDARG00000101380
  
Biological name :cryabb
  
Synonyms : cryabb / crystallin, alpha B, b
  
Possible biological names infered from orthology : Alpha-crystallin B chain / CRYAB / crystallin alpha B / P02511 / P23927
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 57641554
Gene end: 57650998
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000129989
Ensembl peptide - ENSDARP00000141971
Ensembl peptide - ENSDARP00000132828
NCBI entrez gene - 436943     See in Manteia.
RefSeq - NM_001002670
RefSeq Peptide - NP_001002670
swissprot - A0A0R4IY19
swissprot - A0A0R4IG31
swissprot - Q6DG35
ZFIN ID - ZDB-GENE-040718-419
Ensembl - ENSDARG00000101380
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CRYABENSGALG00000007945Gallus gallus
 CRYABENSG00000109846Homo sapiens
 CryabENSMUSG00000032060Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cryaba / crystallin, alpha B, aENSDARG0000004262152
cryaa / crystallin, alpha A / P02489* / CRYAA2* / P24622* / crystallin alpha A2* / Alpha-crystallin A chain *ENSDARG0000005350248
hspb1 / heat shock protein, alpha-crystallin-related, 1 / P14602* / P04792* / Heat shock protein beta-1 * / heat shock protein family B (small) member 1*ENSDARG0000004106536
si:dkey-1k23.3ENSDARG0000010542236
hspb6 / heat shock protein, alpha-crystallin-related, b6 / O14558* / heat shock protein family B (small) member 6*ENSDARG0000007723628
hspb15 / heat shock protein, alpha-crystallin-related, b15ENSDARG0000007841128
hspb2 / heat shock protein, alpha-crystallin-related, b2 / Q16082* / Q99PR8* / HSPB2-C11orf52* / Heat shock protein beta-2 * / HSPB2-C11orf52 readthrough (NMD candidate)* / heat shock prote...ENSDARG0000005245028
hspb8 / heat shock protein b8 / Q9UJY1* / Q9JK92* / Heat shock protein beta-8 * / heat shock protein family B (small) member 8*ENSDARG0000005836524
hspb3 / heat shock protein, alpha-crystallin-related, b3 / Q9QZ57* / Q12988* / Heat shock protein beta-3 * / heat shock protein family B (small) member 3*ENSDARG0000006771419


Protein motifs (from Interpro)
Interpro ID Name
 IPR001436  Alpha crystallin/Heat shock protein
 IPR002068  Alpha crystallin/Hsp20 domain
 IPR003090  Alpha-crystallin, N-terminal
 IPR008978  HSP20-like chaperone
 IPR031107  Small heat shock protein HSP20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0030239 myofibril assembly IMP
 biological_processGO:0060047 heart contraction IMP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0005212 structural constituent of eye lens IEA
 molecular_functionGO:0051082 unfolded protein binding IDA


Pathways (from Reactome)
Pathway description
HSF1-dependent transactivation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle decreased functionality , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000092 axis axis curved , abnormal
axis shortened , abnormal
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 ZFA:0000107 eye eye lens opaque , abnormal
eye lens decreased size , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000471 atrium atrium decreased functionality , abnormal
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 ZFA:0001094 whole organism whole organism decreased mobility , abnormal
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 ZFA:0001115 trunk trunk curved , abnormal
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 ZFA:0005277 skeletal muscle skeletal muscle refractivity , abnormal
skeletal muscle nucleus circular , abnormal
skeletal muscle sarcomere disorganized , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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