ENSGALG00000007945


Gallus gallus

Features
Gene ID: ENSGALG00000007945
  
Biological name :CRYAB
  
Synonyms : Alpha-crystallin B chain / CRYAB / Q05713
  
Possible biological names infered from orthology : crystallin alpha B / P02511 / P23927
  
Species: Gallus gallus
  
Chr. number: 24
Strand: 1
Band:
Gene start: 6212347
Gene end: 6216461
  
Corresponding Affymetrix probe sets: Gga.1999.1.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012892
Ensembl peptide - ENSGALP00000061334
Ensembl peptide - ENSGALP00000053496
NCBI entrez gene - 396089     See in Manteia.
RefSeq - NM_205176
RefSeq Peptide - NP_990507
swissprot - A0A1L1RR96
swissprot - A0A1D5PKY3
swissprot - Q05713
Ensembl - ENSGALG00000007945
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cryabbENSDARG00000101380Danio rerio
 CRYABENSG00000109846Homo sapiens
 CryabENSMUSG00000032060Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRYAA / P02504 / Alpha-crystallin A chain / P24622* / CRYAA2* / P02489* / crystallin alpha A* / crystallin alpha A2*ENSGALG0000001619955
HSPB1 / heat shock protein beta-1 / P04792* / P14602* / heat shock protein family B (small) member 1*ENSGALG0000000192639
HSPB2 / heat shock protein beta-2 / Q99PR8* / Q16082* / HSPB2-C11orf52* / HSPB2-C11orf52 readthrough (NMD candidate)* / heat shock protein family B (small) member 2*ENSGALG0000004084233
HSPB8 / heat shock protein family B (small) member 8 / Q9JK92* / Q9UJY1* / Heat shock protein beta-8 *ENSGALG0000000738326
HSPB3 / heat shock protein family B (small) member 3 / Q12988* / Q9QZ57* / Heat shock protein beta-3 *ENSGALG0000001491219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001436  Alpha crystallin/Heat shock protein
 IPR002068  Alpha crystallin/Hsp20 domain
 IPR003090  Alpha-crystallin, N-terminal
 IPR008978  HSP20-like chaperone
 IPR031107  Small heat shock protein HSP20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0007021 tubulin complex assembly IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010941 regulation of cell death IEA
 biological_processGO:0032387 negative regulation of intracellular transport IEA
 biological_processGO:0032463 negative regulation of protein homooligomerization IEA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0060561 apoptotic process involved in morphogenesis IEA
 biological_processGO:0071480 cellular response to gamma radiation IEA
 biological_processGO:1905907 negative regulation of amyloid fibril formation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0043292 contractile fiber IEA
 molecular_functionGO:0001540 amyloid-beta binding IEA
 molecular_functionGO:0005212 structural constituent of eye lens IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
HSF1-dependent transactivation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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