ENSGALG00000001926


Gallus gallus

Features
Gene ID: ENSGALG00000001926
  
Biological name :HSPB1
  
Synonyms : heat shock protein beta-1 / HSPB1
  
Possible biological names infered from orthology : heat shock protein family B (small) member 1 / P04792 / P14602
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 4228616
Gene end: 4230508
  
Corresponding Affymetrix probe sets: Gga.1809.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039447
NCBI entrez gene - 396227     See in Manteia.
RefSeq - NM_205290
RefSeq Peptide - NP_990621
swissprot - F1P593
Ensembl - ENSGALG00000001926
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hspb1ENSDARG00000041065Danio rerio
 HSPB1ENSG00000106211Homo sapiens
 Hspb1ENSMUSG00000004951Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSPB8 / heat shock protein family B (small) member 8 / Q9JK92* / Q9UJY1* / Heat shock protein beta-8 *ENSGALG0000000738335
CRYAB / Q05713 / Alpha-crystallin B chain / P02511* / P23927* / crystallin alpha B*ENSGALG0000000794535
CRYAA / P02504 / Alpha-crystallin A chain / P24622* / CRYAA2* / P02489* / crystallin alpha A* / crystallin alpha A2*ENSGALG0000001619935
HSPB2 / heat shock protein beta-2 / Q99PR8* / Q16082* / HSPB2-C11orf52* / HSPB2-C11orf52 readthrough (NMD candidate)* / heat shock protein family B (small) member 2*ENSGALG0000004084231
HSPB3 / heat shock protein family B (small) member 3 / Q12988* / Q9QZ57* / Heat shock protein beta-3 *ENSGALG0000001491220


Protein motifs (from Interpro)
Interpro ID Name
 IPR001436  Alpha crystallin/Heat shock protein
 IPR002068  Alpha crystallin/Hsp20 domain
 IPR008978  HSP20-like chaperone
 IPR031107  Small heat shock protein HSP20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0032731 positive regulation of interleukin-1 beta production IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IEA
 biological_processGO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway IEA
 biological_processGO:0042535 positive regulation of tumor necrosis factor biosynthetic process IEA
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0061077 chaperone-mediated protein folding IEA
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IEA
 biological_processGO:0099641 anterograde axonal protein transport IEA
 biological_processGO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:2001028 positive regulation of endothelial cell chemotaxis IEA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0043292 contractile fiber IEA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0005080 protein kinase C binding IEA
 molecular_functionGO:0008426 protein kinase C inhibitor activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IEA


Pathways (from Reactome)
Pathway description
VEGFA-VEGFR2 Pathway
AUF1 (hnRNP D0) binds and destabilizes mRNA
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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