ENSGALG00000016199


Gallus gallus

Features
Gene ID: ENSGALG00000016199
  
Biological name :CRYAA
  
Synonyms : Alpha-crystallin A chain / CRYAA / P02504
  
Possible biological names infered from orthology : CRYAA2 / crystallin alpha A / crystallin alpha A2 / P02489 / P24622
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 109772354
Gene end: 109775958
  
Corresponding Affymetrix probe sets: GgaAffx.10353.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000035906
Ensembl peptide - ENSGALP00000061143
Ensembl peptide - ENSGALP00000054560
NCBI entrez gene - 418546     See in Manteia.
RefSeq - NM_001030797
RefSeq Peptide - NP_001025968
swissprot - A3FMM9
swissprot - A0A1L1RQR7
swissprot - A0A1I7Q440
swissprot - P02504
Ensembl - ENSGALG00000016199
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cryaaENSDARG00000053502Danio rerio
 CRYAAENSG00000160202Homo sapiens
 CRYAA2ENSG00000276076Homo sapiens
 CryaaENSMUSG00000024041Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRYAB / Q05713 / Alpha-crystallin B chain / P02511* / P23927* / crystallin alpha B*ENSGALG0000000794555
HSPB1 / heat shock protein beta-1 / P04792* / P14602* / heat shock protein family B (small) member 1*ENSGALG0000000192639
HSPB2 / heat shock protein beta-2 / Q99PR8* / Q16082* / HSPB2-C11orf52* / HSPB2-C11orf52 readthrough (NMD candidate)* / heat shock protein family B (small) member 2*ENSGALG0000004084227
HSPB8 / heat shock protein family B (small) member 8 / Q9JK92* / Q9UJY1* / Heat shock protein beta-8 *ENSGALG0000000738326
HSPB3 / heat shock protein family B (small) member 3 / Q12988* / Q9QZ57* / Heat shock protein beta-3 *ENSGALG0000001491217


Protein motifs (from Interpro)
Interpro ID Name
 IPR001436  Alpha crystallin/Heat shock protein
 IPR002068  Alpha crystallin/Hsp20 domain
 IPR003090  Alpha-crystallin, N-terminal
 IPR008978  HSP20-like chaperone
 IPR012274  Alpha-crystallin, subunit A
 IPR031107  Small heat shock protein HSP20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0002089 lens morphogenesis in camera-type eye IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007017 microtubule-based process IEA
 biological_processGO:0007021 tubulin complex assembly IEA
 biological_processGO:0007601 visual perception ISS
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0032387 negative regulation of intracellular transport ISS
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IEA
 biological_processGO:0051260 protein homooligomerization ISS
 biological_processGO:0060561 apoptotic process involved in morphogenesis IEA
 biological_processGO:0070141 response to UV-A IEA
 biological_processGO:0070309 lens fiber cell morphogenesis IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome ISS
 molecular_functionGO:0005212 structural constituent of eye lens IEA
 molecular_functionGO:0042802 identical protein binding ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051082 unfolded protein binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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