ENSDARG00000055713


Danio rerio

Features
Gene ID: ENSDARG00000055713
  
Biological name :fmnl1a
  
Synonyms : fmnl1a / formin-like 1a
  
Possible biological names infered from orthology : FMNL1 / formin like 1 / Formin-like protein 1 / O95466 / Q9JL26
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 37196258
Gene end: 37235300
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000126332
Ensembl peptide - ENSDARP00000155643
Ensembl peptide - ENSDARP00000157056
NCBI entrez gene - 557062     See in Manteia.
swissprot - I3ITQ8
ZFIN ID - ZDB-GENE-120215-83
Ensembl - ENSDARG00000055713
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000032155Gallus gallus
 ENSGALG00000032658Gallus gallus
 FMNL1ENSG00000184922Homo sapiens
 Fmnl1ENSMUSG00000055805Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fmnl2a / formin-like 2a / FMNL2* / A2APV2* / Q96PY5* / formin like 2* / Formin-like protein 2 *ENSDARG0000001258653
fmnl2b / formin-like 2b / FMNL2* / A2APV2* / Q96PY5* / formin like 2* / Formin-like protein 2 *ENSDARG0000007504152
fmnl3 / Q6NXC0 / formin-like 3 / Q8IVF7* / Q6ZPF4* / Formin-like protein 3 *ENSDARG0000000437251
CABZ01055365.1 / FMNL1* / O95466* / formin like 1*ENSDARG0000010426325
daam1a / dishevelled associated activator of morphogenesis 1a / DAAM1* / Q8BPM0* / Q9Y4D1* / Disheveled-associated activator of morphosis 1 * / dishevelled associated activator of morphogenesis 1*ENSDARG0000001505924
daam2 / dishevelled associated activator of morphogenesis 2 / Q80U19* / Q86T65* / Disheveled-associated activator of morphosis 2 *ENSDARG0000002839323
daam1b / dishevelled associated activator of morphogenesis 1b / DAAM1* / Q8BPM0* / Q9Y4D1* / Disheveled-associated activator of morphosis 1 * / dishevelled associated activator of morphogenesis 1*ENSDARG0000000968923
diaph2 / diaphanous-related formin 2 / 2 * / O60879* / O70566*ENSDARG0000007606022
diaph3 / diaphanous-related formin 3 / 3 * / Q9NSV4* / Q9Z207*ENSDARG0000009078520
fhdc3 / FH2 domain containing 3ENSDARG0000006912911
fhdc2 / FH2 domain containing 2ENSDARG0000009976710
fhdc1 / FH2 domain containing 1 / Q3ULZ2* / Q9C0D6* / FH2 domain-containing protein 1 *ENSDARG0000007481210
fhdc4 / FH2 domain containing 4ENSDARG0000008626110
fhdc5 / FH2 domain containing 5 / FHDC1* / Q3ULZ2* / Q9C0D6* / FH2 domain containing 1* / FH2 domain-containing protein 1 *ENSDARG000000959629
CABZ01057928.1 / DIAPH1* / O60610* / diaphanous related formin 1*ENSDARG000001150827
CABZ01060373.1 / INF2* / Q27J81* / inverted formin, FH2 and WH2 domain containing*ENSDARG000001170695


Protein motifs (from Interpro)
Interpro ID Name
 IPR010472  Formin, FH3 domain
 IPR010473  Formin, GTPase-binding domain
 IPR011989  Armadillo-like helical
 IPR014767  Diaphanous autoregulatory (DAD) domain
 IPR014768  Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
 IPR015425  Formin, FH2 domain
 IPR016024  Armadillo-type fold
 IPR027657  Formin-like protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0016043 cellular component organization IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037870 actb2 / Q7ZVF9 / actin, beta 2 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / complex
 ENSDARG00000037746 actb1 / Q7ZVI7 / actin, beta 1 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / complex
 ENSDARG00000032161 B0S6J3 / srgap2 / SLIT-ROBO Rho GTPase activating protein 2 / O75044* / Q91Z67* / P0DJJ0* / P0DMP2* / SRGAP2C* / SRGAP2B* / SLIT-ROBO Rho GTPase activating protein 2B* / SLIT-ROBO Rho GTPas...  / complex / reaction
 ENSDARG00000055713 fmnl1a / formin-like 1a / FMNL1* / O95466* / Q9JL26* / formin like 1* / Formin-like protein 1 *  / complex






 

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