ENSDARG00000012586


Danio rerio

Features
Gene ID: ENSDARG00000012586
  
Biological name :fmnl2a
  
Synonyms : fmnl2a / formin-like 2a
  
Possible biological names infered from orthology : A2APV2 / FMNL2 / formin like 2 / Formin-like protein 2 / Q96PY5
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 4730398
Gene end: 4856767
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000024319
Ensembl peptide - ENSDARP00000115853
Ensembl peptide - ENSDARP00000118722
NCBI entrez gene - 100006456     See in Manteia.
swissprot - F1Q6D2
swissprot - F1QDA5
swissprot - F1QKR1
ZFIN ID - ZDB-GENE-081105-70
Ensembl - ENSDARG00000012586
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FMNL2ENSGALG00000012525Gallus gallus
 FMNL2ENSG00000157827Homo sapiens
 Fmnl2ENSMUSG00000036053Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fmnl2b / formin-like 2b / FMNL2* / A2APV2* / Q96PY5* / formin like 2* / Formin-like protein 2 *ENSDARG0000007504178
fmnl3 / Q6NXC0 / formin-like 3 / Q8IVF7* / Q6ZPF4* / Formin-like protein 3 *ENSDARG0000000437266
fmnl1a / formin-like 1a / FMNL1* / O95466* / Q9JL26* / formin like 1* / Formin-like protein 1 *ENSDARG0000005571353
daam1b / dishevelled associated activator of morphogenesis 1b / DAAM1* / Q8BPM0* / Q9Y4D1* / Disheveled-associated activator of morphosis 1 * / dishevelled associated activator of morphogenesis 1*ENSDARG0000000968924
daam1a / dishevelled associated activator of morphogenesis 1a / DAAM1* / Q8BPM0* / Q9Y4D1* / Disheveled-associated activator of morphosis 1 * / dishevelled associated activator of morphogenesis 1*ENSDARG0000001505924
daam2 / dishevelled associated activator of morphogenesis 2 / Q80U19* / Q86T65* / Disheveled-associated activator of morphosis 2 *ENSDARG0000002839323
diaph2 / diaphanous-related formin 2 / 2 * / O60879* / O70566*ENSDARG0000007606021
CABZ01055365.1 / FMNL1* / O95466* / formin like 1*ENSDARG0000010426321
diaph3 / diaphanous-related formin 3 / 3 * / Q9NSV4* / Q9Z207*ENSDARG0000009078520
fhdc1 / FH2 domain containing 1 / Q3ULZ2* / Q9C0D6* / FH2 domain-containing protein 1 *ENSDARG0000007481211
fhdc2 / FH2 domain containing 2ENSDARG0000009976710
fhdc3 / FH2 domain containing 3ENSDARG0000006912910
fhdc4 / FH2 domain containing 4ENSDARG000000862619
fhdc5 / FH2 domain containing 5 / FHDC1* / Q3ULZ2* / Q9C0D6* / FH2 domain containing 1* / FH2 domain-containing protein 1 *ENSDARG000000959628
CABZ01057928.1 / DIAPH1* / O60610* / diaphanous related formin 1*ENSDARG000001150827
CABZ01060373.1 / INF2* / Q27J81* / inverted formin, FH2 and WH2 domain containing*ENSDARG000001170696


Protein motifs (from Interpro)
Interpro ID Name
 IPR010472  Formin, FH3 domain
 IPR010473  Formin, GTPase-binding domain
 IPR011989  Armadillo-like helical
 IPR014767  Diaphanous autoregulatory (DAD) domain
 IPR014768  Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
 IPR015425  Formin, FH2 domain
 IPR016024  Armadillo-type fold
 IPR027656  Formin-like protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0016043 cellular component organization IEA
 biological_processGO:0022604 regulation of cell morphogenesis IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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