ENSGALG00000012525


Gallus gallus

Features
Gene ID: ENSGALG00000012525
  
Biological name :FMNL2
  
Synonyms : FMNL2 / formin like 2
  
Possible biological names infered from orthology : A2APV2 / Formin-like protein 2 / Q96PY5
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 35631158
Gene end: 35735887
  
Corresponding Affymetrix probe sets: Gga.7290.1.S1_at (Chicken Array)   GgaAffx.7949.1.S1_at (Chicken Array)   GgaAffx.7949.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036957
Ensembl peptide - ENSGALP00000050724
Ensembl peptide - ENSGALP00000050630
Ensembl peptide - ENSGALP00000048111
NCBI entrez gene - 771739     See in Manteia.
RefSeq - XM_015290213
RefSeq - XM_015290210
RefSeq - XM_015290211
RefSeq - XM_015290212
swissprot - A0A1D5PD81
swissprot - A0A1D5PCY9
swissprot - A0A1D5P5Y7
swissprot - F1NQH1
Ensembl - ENSGALG00000012525
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fmnl2aENSDARG00000012586Danio rerio
 fmnl2bENSDARG00000075041Danio rerio
 FMNL2ENSG00000157827Homo sapiens
 Fmnl2ENSMUSG00000036053Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FMNL1* / O95466* / Q9JL26* / formin like 1* / Formin-like protein 1 *ENSGALG0000003215532
DAAM1 / Gallus gallus dishevelled associated activator of morphogenesis 1 (DAAM1), mRNA. / Q8BPM0* / Q9Y4D1* / Disheveled-associated activator of morphosis 1 * / dishevelled associated acti...ENSGALG0000001201724
DAAM2 / dishevelled associated activator of morphogenesis 2 / Q80U19* / Q86T65* / Disheveled-associated activator of morphosis 2 *ENSGALG0000001005524
FMNL1* / O95466* / Q9JL26* / formin like 1* / Formin-like protein 1 *ENSGALG0000003265824
DIAPH2 / protein diaphanous homolog 2 / 2 * / O60879* / O70566* / diaphanous related formin 2*ENSGALG0000003079121
INF2 / inverted formin, FH2 and WH2 domain containing / Q27J81*ENSGALG0000001160820
DIAPH3 / diaphanous related formin 3 / 3 * / Q9NSV4* / Q9Z207*ENSGALG0000001693720
FHDC1 / FH2 domain containing 1 / Q3ULZ2* / Q9C0D6* / FH2 domain-containing protein 1 *ENSGALG0000004105410


Protein motifs (from Interpro)
Interpro ID Name
 IPR010472  Formin, FH3 domain
 IPR010473  Formin, GTPase-binding domain
 IPR014767  Diaphanous autoregulatory (DAD) domain
 IPR014768  Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
 IPR015425  Formin, FH2 domain
 IPR016024  Armadillo-type fold
 IPR027656  Formin-like protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0016043 cellular component organization IEA
 biological_processGO:0022604 regulation of cell morphogenesis IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001569 RHOC / Q9PSX7 / Rho-related GTP-binding protein RhoC / Q62159* / P08134* / ras homolog family member C*  / complex / reaction
 ENSGALG00000004796 CDC42 / Q90694 / Cell division control protein 42 homolog / P60766* / P60953* / cell division cycle 42* / Cell division control *  / reaction / complex
 ENSGALG00000012525 FMNL2 / formin like 2 / A2APV2* / Q96PY5* / Formin-like protein 2 *  / complex






 

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