ENSMUSG00000036053


Mus musculus

Features
Gene ID: ENSMUSG00000036053
  
Biological name :Fmnl2
  
Synonyms : A2APV2 / Fmnl2 / Formin-like protein 2
  
Possible biological names infered from orthology : formin like 2 / Q96PY5
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C1.1
Gene start: 52857860
Gene end: 53133804
  
Corresponding Affymetrix probe sets: 10472097 (MoGene1.0st)   1428579_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118658
Ensembl peptide - ENSMUSP00000057084
Ensembl peptide - ENSMUSP00000088472
Ensembl peptide - ENSMUSP00000117822
Ensembl peptide - ENSMUSP00000047260
NCBI entrez gene - 71409     See in Manteia.
MGI - MGI:1918659
RefSeq - XM_017319260
RefSeq - XM_006498333
RefSeq - XM_006498334
RefSeq - XM_006498335
RefSeq - XM_006498336
RefSeq - XM_006498337
RefSeq - XM_006498338
RefSeq - NM_172409
RefSeq - XM_006498330
RefSeq - XM_006498331
RefSeq - XM_006498332
RefSeq Peptide - NP_765997
swissprot - E9PXE6
swissprot - F6XR20
swissprot - F8VPR2
swissprot - A2AQW2
swissprot - A2APV2
Ensembl - ENSMUSG00000036053
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fmnl2aENSDARG00000012586Danio rerio
 fmnl2bENSDARG00000075041Danio rerio
 FMNL2ENSGALG00000012525Gallus gallus
 FMNL2ENSG00000157827Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fmnl3 / Q6ZPF4 / Formin-like protein 3 / Q8IVF7* / formin like 3*ENSMUSG0000002300868
Fmnl1 / Q9JL26 / Formin-like protein 1 / O95466* / formin like 1*ENSMUSG0000005580558
Daam1 / Q8BPM0 / Disheveled-associated activator of morphosis 1 / Q9Y4D1* / dishevelled associated activator of morphogenesis 1*ENSMUSG0000003457425
Daam2 / Q80U19 / Disheveled-associated activator of morphosis 2 / Q86T65* / dishevelled associated activator of morphogenesis 2*ENSMUSG0000004026024
3 / Diaph3 / Q9Z207 / Q9NSV4* / diaphanous related formin 3*ENSMUSG0000002202122
2 / Diaph2 / O70566 / O60879* / diaphanous related formin 2*ENSMUSG0000003448021
1 / Diaph1 / O08808 / O60610* / diaphanous related formin 1*ENSMUSG0000002445621
Inf2 / inverted formin, FH2 and WH2 domain containing / Q27J81*ENSMUSG0000003767920
Fhdc1 / Q3ULZ2 / FH2 domain-containing protein 1 / Q9C0D6* / FH2 domain containing 1*ENSMUSG0000004184211


Protein motifs (from Interpro)
Interpro ID Name
 IPR010472  Formin, FH3 domain
 IPR010473  Formin, GTPase-binding domain
 IPR011989  Armadillo-like helical
 IPR014767  Diaphanous autoregulatory (DAD) domain
 IPR014768  Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
 IPR015425  Formin, FH2 domain
 IPR016024  Armadillo-type fold
 IPR027656  Formin-like protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0016043 cellular component organization IEA
 biological_processGO:0022604 regulation of cell morphogenesis IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002233 Rhoc / Q62159 / Rho-related GTP-binding protein RhoC / P08134* / ras homolog family member C*  / reaction / complex
 ENSMUSG00000036053 Fmnl2 / A2APV2 / Formin-like protein 2 / Q96PY5* / formin like 2*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr