ENSMUSG00000037679


Mus musculus

Features
Gene ID: ENSMUSG00000037679
  
Biological name :Inf2
  
Synonyms : Inf2 / inverted formin, FH2 and WH2 domain containing
  
Possible biological names infered from orthology : Q27J81
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: F1
Gene start: 112588784
Gene end: 112615557
  
Corresponding Affymetrix probe sets: 10398831 (MoGene1.0st)   1432184_a_at (Mouse Genome 430 2.0 Array)   1436216_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000098591
Ensembl peptide - ENSMUSP00000152851
Ensembl peptide - ENSMUSP00000152590
NCBI entrez gene - 70435     See in Manteia.
MGI - MGI:1917685
RefSeq - XM_017315182
RefSeq - NM_198411
RefSeq - XM_006516224
RefSeq Peptide - NP_940803
swissprot - E9QLA5
swissprot - A0A1Y7VLQ6
swissprot - A0A1Y7VM80
Ensembl - ENSMUSG00000037679
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01060373.1ENSDARG00000117069Danio rerio
 INF2ENSGALG00000011608Gallus gallus
 INF2ENSG00000203485Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
1 / Diaph1 / O08808 / O60610* / diaphanous related formin 1*ENSMUSG0000002445621
3 / Diaph3 / Q9Z207 / Q9NSV4* / diaphanous related formin 3*ENSMUSG0000002202119
2 / Diaph2 / O70566 / O60879* / diaphanous related formin 2*ENSMUSG0000003448019
Daam2 / Q80U19 / Disheveled-associated activator of morphosis 2 / Q86T65* / dishevelled associated activator of morphogenesis 2*ENSMUSG0000004026019
Daam1 / Q8BPM0 / Disheveled-associated activator of morphosis 1 / Q9Y4D1* / dishevelled associated activator of morphogenesis 1*ENSMUSG0000003457419
Fmnl2 / A2APV2 / Formin-like protein 2 / Q96PY5* / formin like 2*ENSMUSG0000003605317
Fmnl1 / Q9JL26 / Formin-like protein 1 / O95466* / formin like 1*ENSMUSG0000005580517
Fhdc1 / Q3ULZ2 / FH2 domain-containing protein 1 / Q9C0D6* / FH2 domain containing 1*ENSMUSG0000004184217
Fmnl3 / Q6ZPF4 / Formin-like protein 3 / Q8IVF7* / formin like 3*ENSMUSG0000002300817


Protein motifs (from Interpro)
Interpro ID Name
 IPR003124  WH2 domain
 IPR010472  Formin, FH3 domain
 IPR010473  Formin, GTPase-binding domain
 IPR011989  Armadillo-like helical
 IPR014768  Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
 IPR015425  Formin, FH2 domain
 IPR016024  Armadillo-type fold
 IPR027649  Inverted formin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016043 cellular component organization IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0090140 regulation of mitochondrial fission IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000249 abnormal blood vessel physiology "anomalous function of any of the tubes that convey blood: arteries, arterioles, capallaries, venules, veins" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0002293 long gestation period "increase in the average duration of a pregnancy " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0002842 increased blood pressure "increased tension of the blood within the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0003231 abnormal placental vasculature "malformation in the vessels of the placenta" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93157]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0004201 fetal growth retardation "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0009431 decreased fetal weight "reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

 MP:0011521 decreased placental labyrinth size "reduction in the size of the structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [MGI:csmith]
Show

Allelic Composition: Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi,Krt14tm1(cre)Wbm/Krt14+
Genetic Background: B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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