ENSDARG00000015059


Danio rerio

Features
Gene ID: ENSDARG00000015059
  
Biological name :daam1a
  
Synonyms : daam1a / dishevelled associated activator of morphogenesis 1a
  
Possible biological names infered from orthology : DAAM1 / Disheveled-associated activator of morphosis 1 / dishevelled associated activator of morphogenesis 1 / Q8BPM0 / Q9Y4D1
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 14467015
Gene end: 14591764
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000127933
Ensembl peptide - ENSDARP00000143770
Ensembl peptide - ENSDARP00000132829
Ensembl peptide - ENSDARP00000023227
NCBI entrez gene - 557451     See in Manteia.
RefSeq - XM_017351772
swissprot - E7F6Y9
swissprot - A0A0R4IER9
swissprot - X1WCJ0
ZFIN ID - ZDB-GENE-030911-6
Ensembl - ENSDARG00000015059
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DAAM1ENSGALG00000012017Gallus gallus
 DAAM1ENSG00000100592Homo sapiens
 Daam1ENSMUSG00000034574Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
daam1b / dishevelled associated activator of morphogenesis 1b / DAAM1* / Q8BPM0* / Q9Y4D1* / Disheveled-associated activator of morphosis 1 * / dishevelled associated activator of morphogenesis 1*ENSDARG0000000968982
daam2 / dishevelled associated activator of morphogenesis 2 / Q80U19* / Q86T65* / Disheveled-associated activator of morphosis 2 *ENSDARG0000002839365
diaph2 / diaphanous-related formin 2 / 2 * / O60879* / O70566*ENSDARG0000007606025
fmnl2b / formin-like 2b / FMNL2* / A2APV2* / Q96PY5* / formin like 2* / Formin-like protein 2 *ENSDARG0000007504124
fmnl2a / formin-like 2a / FMNL2* / A2APV2* / Q96PY5* / formin like 2* / Formin-like protein 2 *ENSDARG0000001258624
diaph3 / diaphanous-related formin 3 / 3 * / Q9NSV4* / Q9Z207*ENSDARG0000009078524
fmnl3 / Q6NXC0 / formin-like 3 / Q8IVF7* / Q6ZPF4* / Formin-like protein 3 *ENSDARG0000000437224
fmnl1a / formin-like 1a / FMNL1* / O95466* / Q9JL26* / formin like 1* / Formin-like protein 1 *ENSDARG0000005571324
fhdc4 / FH2 domain containing 4ENSDARG0000008626112
fhdc1 / FH2 domain containing 1 / Q3ULZ2* / Q9C0D6* / FH2 domain-containing protein 1 *ENSDARG0000007481212
fhdc3 / FH2 domain containing 3ENSDARG0000006912912
CABZ01055365.1 / FMNL1* / O95466* / formin like 1*ENSDARG0000010426311
fhdc2 / FH2 domain containing 2ENSDARG0000009976710
fhdc5 / FH2 domain containing 5 / FHDC1* / Q3ULZ2* / Q9C0D6* / FH2 domain containing 1* / FH2 domain-containing protein 1 *ENSDARG000000959629
CABZ01057928.1 / DIAPH1* / O60610* / diaphanous related formin 1*ENSDARG000001150828
CABZ01060373.1 / INF2* / Q27J81* / inverted formin, FH2 and WH2 domain containing*ENSDARG000001170695


Protein motifs (from Interpro)
Interpro ID Name
 IPR010472  Formin, FH3 domain
 IPR010473  Formin, GTPase-binding domain
 IPR011989  Armadillo-like helical
 IPR014767  Diaphanous autoregulatory (DAD) domain
 IPR014768  Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
 IPR015425  Formin, FH2 domain
 IPR016024  Armadillo-type fold
 IPR027650  Disheveled-associated activator of morphogenesis 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016043 cellular component organization IEA
 biological_processGO:0021986 habenula development IMP
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0048793 pronephros development IMP
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA


Pathways (from Reactome)
Pathway description
PCP/CE pathway
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye fused with eye , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct branched , abnormal
pronephric duct undulate , abnormal
pronephric duct in contact with pronephric duct , abnormal
Show

 ZFA:0000151 pronephros pronephros morphology , abnormal
Show

 ZFA:0000197 dorsal habenular nucleus dorsal habenular nucleus neuron projection terminus incomplete structure , abnormal
dorsal habenular nucleus neuron morphology , abnormal
dorsal habenular nucleus neuron projection decreased amount , abnormal
Show

 ZFA:0000213 habenula habenula cytoskeleton organization decreased process quality , abnormal
habenula dendrite decreased volume , abnormal
habenula dendrite truncated , abnormal
habenula filamentous actin disorganized , abnormal
habenula determination of left/right asymmetry in diencephalon process quality , abnormal
Show

 ZFA:0000903 interpeduncular nucleus tegmentum interpeduncular nucleus tegmentum innervation process quality , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region bent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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