ENSDARG00000018566


Danio rerio

Features
Gene ID: ENSDARG00000018566
  
Biological name :flnca
  
Synonyms : filamin C, gamma a (actin binding protein 280) / flnca
  
Possible biological names infered from orthology : filamin C / FLNC / Q14315 / Q8VHX6
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 35019693
Gene end: 35041057
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000046217
Ensembl peptide - ENSDARP00000138996
NCBI entrez gene - 100048921     See in Manteia.
RefSeq - XM_002666936
RefSeq - XM_017354239
swissprot - E7F1L7
swissprot - A0A0R4IUS4
ZFIN ID - ZDB-GENE-070503-1
Ensembl - ENSDARG00000018566
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FLNCENSG00000128591Homo sapiens
 FlncENSMUSG00000068699Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
flncb / filamin C, gamma b (actin binding protein 280) / FLNC* / Q14315* / filamin C*ENSDARG0000001882081
flna / filamin A, alpha (actin binding protein 280) / P21333* / Q8BTM8* / filamin A*ENSDARG0000007420165
CABZ01030862.1ENSDARG0000009837437
flnb / filamin B, beta (actin binding protein 278)ENSDARG0000009228134
syne1b / spectrin repeat containing, nuclear envelope 1b / SYNE1* / Q6ZWR6* / Q8NF91* / spectrin repeat containing nuclear envelope protein 1* / Mus musculus spectrin repeat containing, nuc...ENSDARG0000006306816
syne1a / spectrin repeat containing, nuclear envelope 1a / SYNE1* / Q6ZWR6* / Q8NF91* / spectrin repeat containing nuclear envelope protein 1* / Mus musculus spectrin repeat containing, nuc...ENSDARG0000000949915
si:ch211-207i1.2 / SYNE2* / Q8WXH0* / Q6ZWQ0* / spectrin repeat containing, nuclear envelope 2* / spectrin repeat containing nuclear envelope protein 2*ENSDARG0000003010712
clmn / calmin / Q8C5W0* / Q96JQ2*ENSDARG000000968675
syne2b / spectrin repeat containing, nuclear envelope 2b / SYNE2* / Q8WXH0* / Q6ZWQ0* / spectrin repeat containing, nuclear envelope 2* / spectrin repeat containing nuclear envelope protein 2*ENSDARG000000534844
FP325130.1 / FLNB* / O75369* / filamin B*ENSDARG000001125274
zgc:100997 / CLMN* / calmin* / Q8C5W0* / Q96JQ2*ENSDARG000000436674
si:ch211-137a8.2ENSDARG000000689262
zgc:165653ENSDARG000001047131


Protein motifs (from Interpro)
Interpro ID Name
 IPR001298  Filamin/ABP280 repeat
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR017868  Filamin/ABP280 repeat-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0046716 muscle cell cellular homeostasis IMP
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
Cell-extracellular matrix interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism decreased mobility , abnormal
Show

 ZFA:0001462 somite border somite border myosin complex aggregated , abnormal
somite border mislocalised , abnormal
Show

 ZFA:0005784 striated muscle cell striated muscle cell mitochondrion infiltrative , abnormal
striated muscle cell muscle myosin complex accumulation myoseptum , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell spatial pattern , abnormal
skeletal muscle cell broken , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell broken , abnormal
slow muscle cell non-functional , abnormal
slow muscle cell actin filament irregular spatial pattern , abnormal
slow muscle cell myosin filament irregular spatial pattern , abnormal
slow muscle cell type III intermediate filament irregular spatial pattern , abnormal
Show

 ZFA:0009117 fast muscle cell fast muscle cell contractile fiber disassembled , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037746 actb1 / Q7ZVI7 / actin, beta 1 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / reaction / complex
 ENSDARG00000037870 actb2 / Q7ZVF9 / actin, beta 2 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...  / reaction / complex






 

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