ENSMUSG00000025228


Mus musculus

Features
Gene ID: ENSMUSG00000025228
  
Biological name :Actr1a
  
Synonyms : Actr1a / Alpha-centractin / P61164
  
Possible biological names infered from orthology : ARP1 actin related protein 1 homolog A / P61163
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C3
Gene start: 46376814
Gene end: 46395735
  
Corresponding Affymetrix probe sets: 10468217 (MoGene1.0st)   1415873_a_at (Mouse Genome 430 2.0 Array)   1457970_at (Mouse Genome 430 2.0 Array)   1458696_at (Mouse Genome 430 2.0 Array)   1459855_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039844
NCBI entrez gene - 54130     See in Manteia.
MGI - MGI:1858964
RefSeq - NM_016860
RefSeq Peptide - NP_058556
swissprot - P61164
Ensembl - ENSMUSG00000025228
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACTR1AENSGALG00000008086Gallus gallus
 ACTR1AENSG00000138107Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Actr1b / Q8R5C5 / Beta-centractin / P42025* / ARP1 actin related protein 1 homolog B*ENSMUSG0000003735191
Actb / P60710 / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / POTEJ* / P60709* / P0CG39* / actin beta* / POTE ankyrin domain family member J*ENSMUSG0000002958053
Actc1 / P68033 / Actin, alpha cardiac muscle 1 / P68032*ENSMUSG0000006861453
Acta2 / P62737 / Actin, aortic smooth muscle Actin, aortic smooth muscle, intermediate form / P62736* / actin, alpha 2, smooth muscle, aorta*ENSMUSG0000003578353
Actg1 / P63260 / Actin, cytoplasmic 2 Actin, cytoplasmic 2, N-terminally processed / P63261* / actin gamma 1*ENSMUSG0000006282553
Actg2 / P63268 / Actin, gamma-enteric smooth muscle / P63267* / actin, gamma 2, smooth muscle, enteric*ENSMUSG0000005943053
Acta1 / P68134 / Actin, alpha skeletal muscle / P68133* / actin, alpha 1, skeletal muscle*ENSMUSG0000003197252
Actbl2 / Q8BFZ3 / Beta-actin-like protein 2 / Q562R1* / actin, beta like 2*ENSMUSG0000005519451
Actrt3 / Q8BXF8 / Actin-related protein T3 / Q9BYD9*ENSMUSG0000003773742
Actrt2 / Q9D9L5 / Actin-related protein T2 / Q8TDY3*ENSMUSG0000005127642
Actrt1 / Q9D9J3 / Actin-related protein T1 / Q8TDG2*ENSMUSG0000004661539
Actl7a / Q9QY84 / actin-like 7a / Q9Y615*ENSMUSG0000007097937
Gm498ENSMUSG0000003108537
Actl9 / Q8CG27 / Actin-like protein 9 / Q8TC94* / actin like 9*ENSMUSG0000009251937
Actl7b / Q9QY83 / actin-like 7b / Q9Y614*ENSMUSG0000007098036
Actl11 / actin-like 11ENSMUSG0000006636832


Protein motifs (from Interpro)
Interpro ID Name
 IPR004000  Actin family
 IPR004001  Actin, conserved site
 IPR020902  Actin/actin-like conserved site
 IPR029909  Actin-related protein 1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007283 spermatogenesis IEA
 cellular_componentGO:0002177 manchette IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005869 dynactin complex IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0030137 COPI-coated vesicle IEA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0099738 cell cortex region IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020745 P63005 / Pafah1b1 / platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 / P43034* / platelet activating factor acetylhydrolase 1b regulatory subunit 1*  / complex
 ENSMUSG00000015733 Capza2 / P47754 / F-actin-capping protein subunit alpha-2 / P47755* / capping actin protein of muscle Z-line alpha subunit 2*  / complex
 ENSMUSG00000021076 Actr10 / Q9QZB7 / Actin-related protein 10 / Q9NZ32* / actin related protein 10 homolog*  / complex
 ENSMUSG00000024603 Dctn4 / Q8CBY8 / Mus musculus dynactin 4 (Dctn4), transcript variant 2, mRNA. / Q9UJW0* / dynactin subunit 4*  / complex
 ENSMUSG00000028745 Capzb / P47757 / F-actin-capping protein subunit beta / P47756* / capping actin protein of muscle Z-line beta subunit*  / complex
 ENSMUSG00000041791 Capza3 / P70190 / F-actin-capping protein subunit alpha-3 / Q96KX2* / capping actin protein of muscle Z-line alpha subunit 3*  / complex
 ENSMUSG00000031516 Dctn6 / Q9WUB4 / Dynactin subunit 6 / O00399*  / complex
 ENSMUSG00000030868 Dctn5 / Q9QZB9 / Dynactin subunit 5 / Q9BTE1*  / complex
 ENSMUSG00000027012 O88487 / Dync1i2 / Mus musculus dynein cytoplasmic 1 intermediate chain 2 (Dync1i2), transcript variant 9, mRNA. / Q13409* / dynein cytoplasmic 1 intermediate chain 2*  / complex
 ENSMUSG00000030704 Rab6a / P35279 / RAB6A, member RAS oncogene family / RAB6C* / RAB6D* / Q9H0N0* / P20340* / RAB6C, member RAS oncogene family* / RAB6D, member RAS oncogene family*  / complex / reaction
 ENSMUSG00000025228 Actr1a / P61164 / Alpha-centractin / P61163* / ARP1 actin related protein 1 homolog A*  / complex
 ENSMUSG00000029757 O88485 / Dync1i1 / Cytoplasmic dynein 1 intermediate chain 1 / O14576* / dynein cytoplasmic 1 intermediate chain 1*  / complex
 ENSMUSG00000000420 Galnt1 / O08912 / Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 1 soluble form / Q10472* / polypeptide N-acetylgalactosaminyltransferase 1*  / complex / reaction
 ENSMUSG00000064063 BC048507 / cDNA sequence BC048507 / DYNLL1* / P63167* / dynein light chain LC8-type 1*  / complex
 ENSMUSG00000003452 Bicd1 / Q8BR07 / Protein bicaudal D homolog 1 / Q96G01* / BICD cargo adaptor 1*  / reaction / complex
 ENSMUSG00000018707 Q9JHU4 / Dync1h1 / Cytoplasmic dynein 1 heavy chain 1 / Q14204* / dynein cytoplasmic 1 heavy chain 1*  / complex
 ENSMUSG00000031865 Dctn1 / O08788 / Mus musculus dynactin 1 (Dctn1), transcript variant 4, mRNA. / Q14203* / dynactin subunit 1*  / complex
 ENSMUSG00000035770 Q6PDL0 / Dync1li2 / Cytoplasmic dynein 1 light intermediate chain 2 / O43237* / dynein cytoplasmic 1 light intermediate chain 2*  / complex
 ENSMUSG00000028447 Dctn3 / Q9Z0Y1 / Dynactin subunit 3 / O75935*  / complex
 ENSMUSG00000092329 Q6PB93 / Gm20388 / predicted gene 20388 / GALNT2* / Q10471* / polypeptide N-acetylgalactosaminyltransferase 2*  / reaction / complex
 ENSMUSG00000025410 Dctn2 / Q99KJ8 / Dynactin subunit 2 / Q13561*  / complex
 ENSMUSG00000020483 Dynll2 / Q9D0M5 / Dynein light chain 2, cytoplasmic / Q96FJ2* / dynein light chain LC8-type 2*  / complex
 ENSMUSG00000032435 Q8R1Q8 / Dync1li1 / Cytoplasmic dynein 1 light intermediate chain 1 / Q9Y6G9* / dynein cytoplasmic 1 light intermediate chain 1*  / complex






 

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