ENSGALG00000035773


Gallus gallus

Features
Gene ID: ENSGALG00000035773
  
Biological name :PIK3C3
  
Synonyms : phosphatidylinositol 3-kinase catalytic subunit type 3 / PIK3C3
  
Possible biological names infered from orthology : Q6PF93 / Q8NEB9
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 3992964
Gene end: 4061554
  
Corresponding Affymetrix probe sets: Gga.14304.1.S1_s_at (Chicken Array)   GgaAffx.22715.1.S1_at (Chicken Array)   GgaAffx.22715.2.S1_at (Chicken Array)   GgaAffx.5581.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044143
Ensembl peptide - ENSGALP00000055632
NCBI entrez gene - 100857877     See in Manteia.
RefSeq - XM_004949052
RefSeq - XM_004949050
RefSeq - XM_004949051
RefSeq - XM_003642902
RefSeq - XM_004949049
swissprot - A0A1D5PRV3
swissprot - A0A1D5NUX5
Ensembl - ENSGALG00000035773
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pik3c3ENSDARG00000054829Danio rerio
 PIK3C3ENSG00000078142Homo sapiens
 Pik3c3ENSMUSG00000033628Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PIK3CD / phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform / O00329* / O35904* / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta*ENSGALG0000000258323
PIK3C2A / phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha / O00443*ENSGALG0000000612122
PIK3CB / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta / P42338* / Q8BTI9* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform *ENSGALG0000000550522
PIK3C2B / phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta / O00750*ENSGALG0000003704322
PIK3CA / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha / P42336* / P42337* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform *ENSGALG0000000893421
PIK3CG / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma / P48736* / Q9JHG7* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform *ENSGALG0000000808121
PIK3C2G / phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma / O75747* / phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform 2 *ENSGALG0000001311720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000403  Phosphatidylinositol 3-/4-kinase, catalytic domain
 IPR001263  Phosphoinositide 3-kinase, accessory (PIK) domain
 IPR002420  Phosphatidylinositol 3-kinase, C2 domain
 IPR008290  Phosphatidylinositol 3-kinase, Vps34 type
 IPR011009  Protein kinase-like domain superfamily
 IPR015433  Phosphatidylinositol kinase
 IPR016024  Armadillo-type fold
 IPR018936  Phosphatidylinositol 3/4-kinase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006497 protein lipidation IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0009267 cellular response to starvation IEA
 biological_processGO:0016236 macroautophagy IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032465 regulation of cytokinesis IEA
 biological_processGO:0034497 protein localization to phagophore assembly site IEA
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0042149 cellular response to glucose starvation IEA
 biological_processGO:0045022 early endosome to late endosome transport IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0035032 phosphatidylinositol 3-kinase complex, class III IEA
 cellular_componentGO:0044754 autolysosome IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
Synthesis of PIPs at the Golgi membrane
Synthesis of PIPs at the early endosome membrane
Synthesis of PIPs at the late endosome membrane
RHO GTPases Activate NADPH Oxidases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001678 PRKAB2 / protein kinase AMP-activated non-catalytic subunit beta 2 / O43741* / Q6PAM0* / protein kinase, AMP-activated, beta 2 non-catalytic subunit*  / reaction
 ENSGALG00000020999 DYNLL1 / dynein light chain LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / reaction / complex
 ENSGALG00000005522 DYNLL2 / dynein light chain LC8-type 2 / Q96FJ2* / Q9D0M5* / Dynein light chain 2, cytoplasmic *  / reaction / complex
 ENSGALG00000007373 PRKAB1 / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-activated, beta 1 non-catalytic subunit*  / reaction
 ENSGALG00000008347 ATG13 / autophagy related 13 / O75143* / Q91YI1* / Mus musculus autophagy related 13 (Atg13), transcript variant 4, mRNA.*  / reaction
 ENSGALG00000015259 RB1CC1 / RB1 inducible coiled-coil 1 / Q8TDY2* / Q9ESK9* / RB1-inducible coiled-coil protein 1 *  / reaction
 ENSGALG00000014832 PRKAA1 / protein kinase AMP-activated catalytic subunit alpha 1 / Q13131* / Q5EG47* / protein kinase, AMP-activated, alpha 1 catalytic subunit*  / reaction
 ENSGALG00000010826 PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2 / P54646* / Q8BRK8* / protein kinase, AMP-activated, alpha 2 catalytic subunit*  / reaction
 ENSGALG00000011360 PRKAG3 / 5-AMP-activated protein kinase subunit gamma-3 / Q9UGI9* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-activated, gamma 3 non-catat...  / reaction
 ENSGALG00000036282 O54950* / P54619* / PRKAG1* / protein kinase AMP-activated non-catalytic subunit gamma 1* / protein kinase, AMP-activated, gamma 1 non-catalytic subunit*  / reaction
 ENSGALG00000012148 ATG14 / autophagy related 14 / Q6ZNE5* / Q8CDJ3* / Beclin 1-associated autophagy-related key regulator *  / complex






 

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