ENSDARG00000020086


Danio rerio

Features
Gene ID: ENSDARG00000020086
  
Biological name :nuak1a
  
Synonyms : nuak1a / NUAK family, SNF1-like kinase, 1a
  
Possible biological names infered from orthology : NUAK1 / NUAK family kinase 1 / NUAK family SNF1-like kinase 1 / O60285 / Q641K5
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 14360372
Gene end: 14372843
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000025528
NCBI entrez gene - 561563     See in Manteia.
swissprot - F1R343
ZFIN ID - ZDB-GENE-041210-122
Ensembl - ENSDARG00000020086
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NUAK1ENSGALG00000012662Gallus gallus
 NUAK1ENSG00000074590Homo sapiens
 Nuak1ENSMUSG00000020032Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nuak1b / NUAK family, SNF1-like kinase, 1b / NUAK1* / Q641K5* / O60285* / NUAK family kinase 1* / NUAK family SNF1-like kinase 1 *ENSDARG0000002867670
nuak2 / NUAK family, SNF1-like kinase, 2 / Q8BZN4* / Q9H093* / NUAK family kinase 2*ENSDARG0000006366147
si:ch211-117c9.1ENSDARG0000009017929
prkaa2 / protein kinase, AMP-activated, alpha 2 catalytic subunit / P54646* / protein kinase AMP-activated catalytic subunit alpha 2*ENSDARG0000006064125
prkaa1 / protein kinase, AMP-activated, alpha 1 catalytic subunit / Q13131* / Q5EG47* / protein kinase AMP-activated catalytic subunit alpha 1*ENSDARG0000006059625
trib3 / tribbles pseudokinase 3 / Q8K4K2* / Q96RU7* / Tribbles homolog 3 *ENSDARG0000001620014
trib1 / tribbles pseudokinase 1 / Q96RU8*ENSDARG0000011096313
stk40 / serine/threonine kinase 40 / Q8N2I9*ENSDARG0000009813513
trib2 / tribbles pseudokinase 2 / Q92519*ENSDARG0000006817910


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction / complex






 

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