ENSMUSG00000039754


Mus musculus

Features
Gene ID: ENSMUSG00000039754
  
Biological name :Alkbh4
  
Synonyms : Alkbh4 / Mus musculus alkB homolog 4, lysine demethylase (Alkbh4), transcript variant 1, mRNA. / Q9D8F1
  
Possible biological names infered from orthology : alkB homolog 4, lysine demethylase / Q9NXW9
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 136136146
Gene end: 136141615
  
Corresponding Affymetrix probe sets: 10526487 (MoGene1.0st)   1429850_x_at (Mouse Genome 430 2.0 Array)   1451432_x_at (Mouse Genome 430 2.0 Array)   1453301_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040403
Ensembl peptide - ENSMUSP00000116402
Ensembl peptide - ENSMUSP00000117167
Ensembl peptide - ENSMUSP00000119887
Ensembl peptide - ENSMUSP00000098134
NCBI entrez gene - 72041     See in Manteia.
MGI - MGI:1919291
RefSeq - XM_006504505
RefSeq - NM_001347492
RefSeq - NM_001359416
RefSeq - NM_028070
RefSeq - XM_006504502
RefSeq - XM_006504503
RefSeq - XM_006504504
RefSeq Peptide - NP_001334421
RefSeq Peptide - NP_001346345
RefSeq Peptide - NP_082346
RefSeq Peptide - NP_001346344
swissprot - D3Z7X9
swissprot - Q9D8F1
swissprot - F7B4H2
swissprot - D6RFB6
Ensembl - ENSMUSG00000039754
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 alkbh4ENSDARG00000052247Danio rerio
 ALKBH4ENSGALG00000001844Gallus gallus
 ALKBH4ENSG00000160993Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR032857  Alpha-ketoglutarate-dependent dioxygenase alkB homologue 4
 IPR037151  Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006482 protein demethylation ISS
 biological_processGO:0031032 actomyosin structure organization ISS
 biological_processGO:0036090 cleavage furrow ingression ISO
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070988 demethylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030496 midbody ISO
 cellular_componentGO:0070938 contractile ring ISS
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003707 increased nucleus count "greater than one nuclei present per cell body when one is expected; often due to failed cytokinesis" [pg:Philip Groth submission]
Show

Allelic Composition: Cavin3tm1(KOMP)Vlcg/Cavin3tm1(KOMP)Vlcg,Cavin2tm1(KOMP)Vlcg/Cavin2tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0004046 abnormal mitosis "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cavin3tm1(KOMP)Vlcg/Cavin3tm1(KOMP)Vlcg,Cavin2tm1(KOMP)Vlcg/Cavin2tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Cavin3tm1(KOMP)Vlcg/Cavin3tm1(KOMP)Vlcg,Cavin2tm1(KOMP)Vlcg/Cavin2tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0011708 decreased fibroblast cell migration "reduced frequency of or less rapid cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium" [MGI:csmith]
Show

Allelic Composition: Cavin3tm1(KOMP)Vlcg/Cavin3tm1(KOMP)Vlcg,Cavin2tm1(KOMP)Vlcg/Cavin2tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6 * C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr