ENSMUSG00000040351


Mus musculus

Features
Gene ID: ENSMUSG00000040351
  
Biological name :Ankib1
  
Synonyms : Ankib1 / Ankyrin repeat and IBR domain-containing protein 1 / Q6ZPS6
  
Possible biological names infered from orthology : ankyrin repeat and IBR domain containing 1 / Q9P2G1
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: A1
Gene start: 3690000
Gene end: 3802925
  
Corresponding Affymetrix probe sets: 10527896 (MoGene1.0st)   1429193_at (Mouse Genome 430 2.0 Array)   1430160_at (Mouse Genome 430 2.0 Array)   1437768_at (Mouse Genome 430 2.0 Array)   1442136_at (Mouse Genome 430 2.0 Array)   1447985_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040946
Ensembl peptide - ENSMUSP00000142687
NCBI entrez gene - 70797     See in Manteia.
MGI - MGI:1918047
RefSeq - NM_001289529
RefSeq - XM_017321097
RefSeq - NM_001003909
RefSeq - NM_001289527
RefSeq - NM_001289528
RefSeq Peptide - NP_001003909
RefSeq Peptide - NP_001276456
RefSeq Peptide - NP_001276457
RefSeq Peptide - NP_001276458
swissprot - Q6ZPS6
swissprot - A0A0G2JEA0
Ensembl - ENSMUSG00000040351
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ankib1bENSDARG00000076829Danio rerio
 Q1L8G6ENSDARG00000060768Danio rerio
 ANKIB1ENSGALG00000031917Gallus gallus
 ANKIB1ENSG00000001629Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arih1 / Q9Z1K5 / E3 ubiquitin-protein ligase ARIH1 / Q9Y4X5* / ariadne RBR E3 ubiquitin protein ligase 1*ENSMUSG0000002523414
Arih2 / Q9Z1K6 / Mus musculus ariadne RBR E3 ubiquitin protein ligase 2 (Arih2), transcript variant 2, mRNA. / O95376* / ariadne RBR E3 ubiquitin protein ligase 2*ENSMUSG0000006414513


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR002110  Ankyrin repeat
 IPR002867  IBR domain
 IPR003903  Ubiquitin interacting motif
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR020683  Ankyrin repeat-containing domain
 IPR031127  E3 ubiquitin ligase RBR family
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0000151 ubiquitin ligase complex IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Alpk3tm1b(EUCOMM)Hmgu/Alpk3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Alpk3tm1b(EUCOMM)Hmgu/H

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Alpk3tm1b(EUCOMM)Hmgu/Alpk3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Alpk3tm1b(EUCOMM)Hmgu/H

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Alpk3tm1b(EUCOMM)Hmgu/Alpk3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Alpk3tm1b(EUCOMM)Hmgu/H

 MP:0013279 increased fasted circulating glucose level "increase in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
Show

Allelic Composition: Alpk3tm1b(EUCOMM)Hmgu/Alpk3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Alpk3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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