ENSMUSG00000040414


Mus musculus

Features
Gene ID: ENSMUSG00000040414
  
Biological name :Slc25a28
  
Synonyms : Q8R0Z5 / Slc25a28 / solute carrier family 25, member 28
  
Possible biological names infered from orthology : Q96A46
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C3
Gene start: 43663822
Gene end: 43674881
  
Corresponding Affymetrix probe sets: 10467852 (MoGene1.0st)   1424776_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000036913
NCBI entrez gene - 246696     See in Manteia.
MGI - MGI:2180509
RefSeq - NM_145156
RefSeq - XM_006527098
RefSeq Peptide - NP_660138
swissprot - Q8R0Z5
Ensembl - ENSMUSG00000040414
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc25a28ENSDARG00000052994Danio rerio
 SLC25A28ENSGALG00000007479Gallus gallus
 Q96A46ENSG00000155287Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q920G8 / Slc25a37 / solute carrier family 25, member 37 / Q9NYZ2*ENSMUSG0000003424859
Q920G8 / Gm16867 / Mitoferrin-1 ENSMUSG000000939549


Protein motifs (from Interpro)
Interpro ID Name
 IPR018108  Mitochondrial substrate/solute carrier
 IPR023395  Mitochondrial carrier domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006839 mitochondrial transport IBA
 biological_processGO:0048250 iron import into the mitochondrion IBA
 biological_processGO:0055072 iron ion homeostasis IBA
 biological_processGO:1903874 ferrous iron transmembrane transport IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005381 iron ion transmembrane transporter activity IBA
 molecular_functionGO:0015093 ferrous iron transmembrane transporter activity EXP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J

 MP:0008174 decreased follicular B cell number "reduced number of resting mature B cells with distinct phenotypic characteristics (CD23-positive, CD21-positive) found typically in the B cell follicle region of the spleen and lymph nodes" [CL:0000843, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J

 MP:0008181 increased marginal zone B cell number "greater number of CD23-negative, CD21-positive B cells of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL" [CL:0000845, ISBN:0781735149]
Show

Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J

 MP:0012767 increased KLRG1-positive NK cell number "increase in the number of KLRG1 positive NK cells that represent a maturation subset of NK cells and is linked to NK cell proliferation" [MGI:Annie_Speak, PMID:19479342]
Show

Allelic Composition: Slc24a5tm1b(KOMP)Mbp/Slc24a5tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Slc24a5tm1b(KOMP)Mbp/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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