ENSMUSG00000040463


Mus musculus

Features
Gene ID: ENSMUSG00000040463
  
Biological name :Mybbp1a
  
Synonyms : Myb-binding protein 1A / Mybbp1a / Q7TPV4
  
Possible biological names infered from orthology : Q9BQG0
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B4
Gene start: 72441355
Gene end: 72451768
  
Corresponding Affymetrix probe sets: 10378088 (MoGene1.0st)   1423430_at (Mouse Genome 430 2.0 Array)   1423431_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000044827
NCBI entrez gene - 18432     See in Manteia.
MGI - MGI:106181
RefSeq - NM_016776
RefSeq Peptide - NP_058056
swissprot - Q3U2W2
swissprot - Q7TPV4
Ensembl - ENSMUSG00000040463
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mybbp1aENSDARG00000078214Danio rerio
 MYBBP1AENSGALG00000001363Gallus gallus
 Q9BQG0ENSG00000132382Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007015  DNA polymerase V
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006913 nucleocytoplasmic transport IDA
 biological_processGO:0022904 respiratory electron transport chain IDA
 biological_processGO:0032922 circadian regulation of gene expression IDA
 biological_processGO:0042149 cellular response to glucose starvation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0071158 positive regulation of cell cycle arrest IEA
 biological_processGO:0071897 DNA biosynthetic process IEA
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IEA
 biological_processGO:2000210 positive regulation of anoikis IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0042564 NLS-dependent protein nuclear import complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0001047 core promoter binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0003887 DNA-directed DNA polymerase activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding TAS
 molecular_functionGO:0008270 zinc ion binding TAS
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
Show

Allelic Composition: Mmp9tm1b(EUCOMM)Wtsi/Mmp9tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mmp9tm1b(EUCOMM)Wtsi/Ics

 MP:0002953 thick ventricular wall "increased depth of the cardiac wall of the heart ventricles" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mmp9tm1b(EUCOMM)Wtsi/Mmp9tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mmp9tm1b(EUCOMM)Wtsi/Ics

 MP:0009781 abnormal preimplantation embryo development "an anomaly in the developmental progress of an embryo from 2 cell to blastocyst affecting the viability or number of embryos" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Selenoptm3.1Rfb/Selenoptm3.1Rfb,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * DBA

 MP:0010580 decreased heart left ventricle size "less than average size of the left ventricle compared to the average for a particular population" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mmp9tm1b(EUCOMM)Wtsi/Mmp9tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mmp9tm1b(EUCOMM)Wtsi/Ics

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Selenoptm3.1Rfb/Selenoptm3.1Rfb,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * DBA

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Mmp9tm1b(EUCOMM)Wtsi/Mmp9tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mmp9tm1b(EUCOMM)Wtsi/Ics

 MP:0012129 failure of blastocyst formation "inability to form a blastocyst from a solid ball of cells known as a morula" [MGI:anna]
Show

Allelic Composition: Selenoptm3.1Rfb/Selenoptm3.1Rfb,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * DBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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