ENSMUSG00000040521


Mus musculus

Features
Gene ID: ENSMUSG00000040521
  
Biological name :Tsfm
  
Synonyms : Q9CZR8 / Tsfm / Ts translation elongation factor, mitochondrial
  
Possible biological names infered from orthology : P43897
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 127011572
Gene end: 127030840
  
Corresponding Affymetrix probe sets: 10373009 (MoGene1.0st)   1432170_at (Mouse Genome 430 2.0 Array)   1452698_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122669
Ensembl peptide - ENSMUSP00000042134
Ensembl peptide - ENSMUSP00000113446
NCBI entrez gene - 66399     See in Manteia.
MGI - MGI:1913649
RefSeq - NM_025537
RefSeq Peptide - NP_079813
swissprot - D3Z4M7
swissprot - Q9CX33
swissprot - Q9CZR8
Ensembl - ENSMUSG00000040521
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tsfmENSDARG00000060748Danio rerio
 TSFMENSG00000123297Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001816  Translation elongation factor EFTs/EF1B
 IPR009060  UBA-like superfamily
 IPR014039  Translation elongation factor EFTs/EF1B, dimerisation
 IPR018101  Translation elongation factor Ts, conserved site
 IPR036402  Elongation factor Ts, dimerisation domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006414 translational elongation IEA
 biological_processGO:0070125 mitochondrial translational elongation IBA
 biological_processGO:0070129 regulation of mitochondrial translation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IBA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tcf7l2tm1a(EUCOMM)Wtsi/Tcf7l2+
Genetic Background: C57BL/6N-Tcf7l2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0005103 abnormal retinal pigmentation "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tcf7l2tm1a(EUCOMM)Wtsi/Tcf7l2+
Genetic Background: C57BL/6N-Tcf7l2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Trip13tm1.1(KOMP)Vlcg/Trip13tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Trip13tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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