ENSMUSG00000041161


Mus musculus

Features
Gene ID: ENSMUSG00000041161
  
Biological name :Otud3
  
Synonyms : B1AZ99 / Otud3 / OTU domain-containing protein 3
  
Possible biological names infered from orthology : OTU deubiquitinase 3 / Q5T2D3
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D3
Gene start: 138895379
Gene end: 138913945
  
Corresponding Affymetrix probe sets: 10517666 (MoGene1.0st)   1430046_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000095441
NCBI entrez gene - 73162     See in Manteia.
MGI - MGI:1920412
RefSeq - XM_017320408
RefSeq - NM_028453
RefSeq - XM_017320406
RefSeq - XM_017320407
RefSeq - XM_017320405
RefSeq Peptide - NP_082729
swissprot - B1AZ99
Ensembl - ENSMUSG00000041161
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 otud3ENSDARG00000022648Danio rerio
 OTUD3ENSGALG00000043920Gallus gallus
 OTUD3ENSG00000169914Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003323  OTU domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0035871 protein K11-linked deubiquitination IEA
 biological_processGO:0044313 protein K6-linked deubiquitination IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 biological_processGO:0071108 protein K48-linked deubiquitination ISO
 biological_processGO:1990167 protein K27-linked deubiquitination ISO
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Ovarian tumor domain proteases
Regulation of PTEN stability and activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000013663 Pten / O08586 / phosphatase and tensin homolog / P60484*  / reaction






 

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