ENSMUSG00000041482


Mus musculus

Features
Gene ID: ENSMUSG00000041482
  
Biological name :Piezo2
  
Synonyms : Piezo2 / Piezo-type mechanosensitive ion channel component 2 / Q8CD54
  
Possible biological names infered from orthology : Q9H5I5
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: E1
Gene start: 63010213
Gene end: 63387183
  
Corresponding Affymetrix probe sets: 10459335 (MoGene1.0st)   10459353 (MoGene1.0st)   10459363 (MoGene1.0st)   1430736_at (Mouse Genome 430 2.0 Array)   1442115_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138758
Ensembl peptide - ENSMUSP00000138170
Ensembl peptide - ENSMUSP00000138754
Ensembl peptide - ENSMUSP00000036099
Ensembl peptide - ENSMUSP00000040019
Ensembl peptide - ENSMUSP00000117107
NCBI entrez gene - 667742     See in Manteia.
MGI - MGI:1918781
RefSeq - XM_006526173
RefSeq - NM_001039485
RefSeq - XM_006526166
RefSeq - XM_006526167
RefSeq - XM_006526168
RefSeq - XM_006526169
RefSeq - XM_006526170
RefSeq - XM_006526172
RefSeq Peptide - NP_001034574
swissprot - E9QNW4
swissprot - F6YYK4
swissprot - S4R1C9
swissprot - S4R2R6
swissprot - S4R2S0
swissprot - Q8CD54
Ensembl - ENSMUSG00000041482
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU179656.1ENSDARG00000107086Danio rerio
 LO018508.1ENSDARG00000112723Danio rerio
 piezo2a.2ENSDARG00000076005Danio rerio
 PIEZO2ENSG00000154864Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Piezo1 / Mus musculus piezo-type mechanosensitive ion channel component 1 (Piezo1), transcript variant 1, mRNA. / Q92508* / piezo type mechanosensitive ion channel component 1*ENSMUSG0000001444441


Protein motifs (from Interpro)
Interpro ID Name
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR027272  Piezo family
 IPR031334  Piezo non-specific cation channel, R-Ras-binding domain
 IPR031805  Piezo domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IMP
 biological_processGO:0009612 response to mechanical stimulus IMP
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IDA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050974 detection of mechanical stimulus involved in sensory perception IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071260 cellular response to mechanical stimulus IBA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005261 cation channel activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008381 mechanosensitive ion channel activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002272 abnormal nervous system electrophysiology "anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gtpbp2nmf205/Gtpbp2nmf205,Tg(n-TRtct5)574Slac/0
Genetic Background: involves: C57BL/6J

 MP:0002734 abnormal mechanical nociception "abnormal capability to sense pain elicited by mechanical stimulation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gtpbp2nmf205/Gtpbp2nmf205,Tg(n-TRtct5)574Slac/0
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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