ENSMUSG00000041608


Mus musculus

Features
Gene ID: ENSMUSG00000041608
  
Biological name :Entpd3
  
Synonyms : ectonucleoside triphosphate diphosphohydrolase 3 / Entpd3
  
Possible biological names infered from orthology : O75355
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F4
Gene start: 120539818
Gene end: 120568327
  
Corresponding Affymetrix probe sets: 10590306 (MoGene1.0st)   1434049_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000036830
NCBI entrez gene - 215446     See in Manteia.
MGI - MGI:1321386
RefSeq - NM_178676
RefSeq Peptide - NP_848791
swissprot - Q8BFW6
Ensembl - ENSMUSG00000041608
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 entpd3ENSDARG00000035309Danio rerio
 ENTPD3ENSGALG00000030493Gallus gallus
 ENTPD3ENSG00000168032Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Entpd2 / O55026 / Ectonucleoside triphosphate diphosphohydrolase 2 / Q9Y5L3*ENSMUSG0000001508538
Entpd8 / Q8K0L2 / Ectonucleoside triphosphate diphosphohydrolase 8 / Q5MY95*ENSMUSG0000003681337
Entpd1 / P55772 / Ectonucleoside triphosphate diphosphohydrolase 1 / P49961* / AL365273.2*ENSMUSG0000004812036
Entpd7 / Q3TCT4 / Ectonucleoside triphosphate diphosphohydrolase 7 / Q9NQZ7*ENSMUSG0000002519225
Entpd4 / Q9DBT4 / Ectonucleoside triphosphate diphosphohydrolase 4 / Q9Y227*ENSMUSG0000009546323
Q9DBT4 / Entpd4b / Ectonucleoside triphosphate diphosphohydrolase 4 / ENTPD4* / Q9Y227*ENSMUSG0000002206623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000407  Nucleoside phosphatase GDA1/CD39


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009134 nucleoside diphosphate catabolic process IDA
 biological_processGO:0009143 nucleoside triphosphate catabolic process IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity IDA
 molecular_functionGO:0017111 nucleoside-triphosphatase activity IDA
 molecular_functionGO:0102485 dATP phosphohydrolase activity IEA
 molecular_functionGO:0102486 dCTP phosphohydrolase activity IEA
 molecular_functionGO:0102487 dUTP phosphohydrolase activity IEA
 molecular_functionGO:0102488 dTTP phosphohydrolase activity IEA
 molecular_functionGO:0102489 GTP phosphohydrolase activity IEA
 molecular_functionGO:0102490 8-oxo-dGTP phosphohydrolase activity IEA
 molecular_functionGO:0102491 dGTP phosphohydrolase activity IEA


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NTPDase proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000966 reduced sensory neuron number "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
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Allelic Composition: Mir34atm1.2Arte/Mir34atm1.2Arte,Tg(Neurod2-Smo*A1)199Jols/0
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0010073 decreased pruritus "absence or decreased intensity of an uncomfortable sensation resulting from irritation of the skin or mucous membranes that evokes the desire or reflex to rub or scratch" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Mir34atm1.2Arte/Mir34atm1.2Arte,Tg(Neurod2-Smo*A1)199Jols/0
Genetic Background: involves: C57BL/6 * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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