ENSG00000168032


Homo sapiens

Features
Gene ID: ENSG00000168032
  
Biological name :ENTPD3
  
Synonyms : ectonucleoside triphosphate diphosphohydrolase 3 / ENTPD3 / O75355
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p22.1
Gene start: 40387156
Gene end: 40428619
  
Corresponding Affymetrix probe sets: 1555118_at (Human Genome U133 Plus 2.0 Array)   206191_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406555
Ensembl peptide - ENSP00000301825
Ensembl peptide - ENSP00000401565
Ensembl peptide - ENSP00000404671
NCBI entrez gene - 956     See in Manteia.
OMIM - 603161
RefSeq - NM_001248
RefSeq - NM_001291960
RefSeq - NM_001291961
RefSeq Peptide - NP_001239
RefSeq Peptide - NP_001278889
RefSeq Peptide - NP_001278890
swissprot - O75355
swissprot - C9J0J3
Ensembl - ENSG00000168032
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 entpd3ENSDARG00000035309Danio rerio
 ENTPD3ENSGALG00000030493Gallus gallus
 Entpd3ENSMUSG00000041608Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENTPD2 / Q9Y5L3 / ectonucleoside triphosphate diphosphohydrolase 2ENSG0000005417937
ENTPD1 / P49961 / ectonucleoside triphosphate diphosphohydrolase 1ENSG0000013818535
ENTPD8 / Q5MY95 / ectonucleoside triphosphate diphosphohydrolase 8ENSG0000018883334
ENTPD4 / Q9Y227 / ectonucleoside triphosphate diphosphohydrolase 4ENSG0000019721725
ENTPD7 / Q9NQZ7 / ectonucleoside triphosphate diphosphohydrolase 7ENSG0000019801824
AL365273.2ENSG000002700994


Protein motifs (from Interpro)
Interpro ID Name
 IPR000407  Nucleoside phosphatase GDA1/CD39


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009134 nucleoside diphosphate catabolic process IEA
 biological_processGO:0009143 nucleoside triphosphate catabolic process IEA
 biological_processGO:0034656 nucleobase-containing small molecule catabolic process TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity TAS
 molecular_functionGO:0017111 nucleoside-triphosphatase activity TAS
 molecular_functionGO:0102485 dATP phosphohydrolase activity IEA
 molecular_functionGO:0102486 dCTP phosphohydrolase activity IEA
 molecular_functionGO:0102487 dUTP phosphohydrolase activity IEA
 molecular_functionGO:0102488 dTTP phosphohydrolase activity IEA
 molecular_functionGO:0102489 GTP phosphohydrolase activity IEA
 molecular_functionGO:0102490 8-oxo-dGTP phosphohydrolase activity IEA
 molecular_functionGO:0102491 dGTP phosphohydrolase activity IEA


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NTPDase proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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