ENSG00000188833


Homo sapiens

Features
Gene ID: ENSG00000188833
  
Biological name :ENTPD8
  
Synonyms : ectonucleoside triphosphate diphosphohydrolase 8 / ENTPD8 / Q5MY95
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.3
Gene start: 137434364
Gene end: 137441816
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000344089
Ensembl peptide - ENSP00000360561
Ensembl peptide - ENSP00000420099
Ensembl peptide - ENSP00000420531
NCBI entrez gene - 377841     See in Manteia.
OMIM - 616748
RefSeq - XM_011518668
RefSeq - NM_001033113
RefSeq - NM_198585
RefSeq - XM_011518665
RefSeq - XM_011518666
RefSeq Peptide - NP_001028285
RefSeq Peptide - NP_940987
swissprot - Q5MY95
swissprot - H7C5J8
Ensembl - ENSG00000188833
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 entpd8ENSDARG00000005565Danio rerio
 ENSGALG00000008936Gallus gallus
 ENTPD8ENSGALG00000008932Gallus gallus
 Entpd8ENSMUSG00000036813Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENTPD2 / Q9Y5L3 / ectonucleoside triphosphate diphosphohydrolase 2ENSG0000005417943
ENTPD1 / P49961 / ectonucleoside triphosphate diphosphohydrolase 1ENSG0000013818542
ENTPD3 / O75355 / ectonucleoside triphosphate diphosphohydrolase 3ENSG0000016803237
ENTPD4 / Q9Y227 / ectonucleoside triphosphate diphosphohydrolase 4ENSG0000019721725
ENTPD7 / Q9NQZ7 / ectonucleoside triphosphate diphosphohydrolase 7ENSG0000019801825
AL365273.2ENSG000002700995


Protein motifs (from Interpro)
Interpro ID Name
 IPR000407  Nucleoside phosphatase GDA1/CD39


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009124 nucleoside monophosphate biosynthetic process IEA
 biological_processGO:0009133 nucleoside diphosphate biosynthetic process IEA
 biological_processGO:0034656 nucleobase-containing small molecule catabolic process TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity IEA
 molecular_functionGO:0017111 nucleoside-triphosphatase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0102485 dATP phosphohydrolase activity IEA
 molecular_functionGO:0102486 dCTP phosphohydrolase activity IEA
 molecular_functionGO:0102487 dUTP phosphohydrolase activity IEA
 molecular_functionGO:0102488 dTTP phosphohydrolase activity IEA
 molecular_functionGO:0102489 GTP phosphohydrolase activity IEA
 molecular_functionGO:0102490 8-oxo-dGTP phosphohydrolase activity IEA
 molecular_functionGO:0102491 dGTP phosphohydrolase activity IEA


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NTPDase proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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