ENSG00000054179


Homo sapiens

Features
Gene ID: ENSG00000054179
  
Biological name :ENTPD2
  
Synonyms : ectonucleoside triphosphate diphosphohydrolase 2 / ENTPD2 / Q9Y5L3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.3
Gene start: 137048098
Gene end: 137054045
  
Corresponding Affymetrix probe sets: 207372_s_at (Human Genome U133 Plus 2.0 Array)   230430_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000312494
Ensembl peptide - ENSP00000347213
NCBI entrez gene - 954     See in Manteia.
OMIM - 602012
RefSeq - XM_011519212
RefSeq - NM_001246
RefSeq - NM_203468
RefSeq Peptide - NP_982293
RefSeq Peptide - NP_001237
swissprot - Q9Y5L3
Ensembl - ENSG00000054179
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 entpd2a.1ENSDARG00000035506Danio rerio
 entpd2a.2ENSDARG00000033953Danio rerio
 entpd2bENSDARG00000044795Danio rerio
 ENSGALG00000023909Gallus gallus
 ENTPD2ENSGALG00000039696Gallus gallus
 Entpd2ENSMUSG00000015085Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENTPD8 / Q5MY95 / ectonucleoside triphosphate diphosphohydrolase 8ENSG0000018883343
ENTPD3 / O75355 / ectonucleoside triphosphate diphosphohydrolase 3ENSG0000016803240
ENTPD1 / P49961 / ectonucleoside triphosphate diphosphohydrolase 1ENSG0000013818539
ENTPD7 / Q9NQZ7 / ectonucleoside triphosphate diphosphohydrolase 7ENSG0000019801827
ENTPD4 / Q9Y227 / ectonucleoside triphosphate diphosphohydrolase 4ENSG0000019721726
AL365273.2ENSG000002700993


Protein motifs (from Interpro)
Interpro ID Name
 IPR000407  Nucleoside phosphatase GDA1/CD39


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0009181 purine ribonucleoside diphosphate catabolic process IEA
 biological_processGO:0030168 platelet activation IEA
 biological_processGO:0034656 nucleobase-containing small molecule catabolic process TAS
 cellular_componentGO:0005605 basal lamina IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity IEA
 molecular_functionGO:0017111 nucleoside-triphosphatase activity EXP


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NTPDase proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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