ENSMUSG00000044442


Mus musculus

Features
Gene ID: ENSMUSG00000044442
  
Biological name :N6amt1
  
Synonyms : N-6 adenine-specific DNA methyltransferase 1 (putative) / N6amt1
  
Possible biological names infered from orthology : N-6 adenine-specific DNA methyltransferase 1 / Q9Y5N5
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: C3.3
Gene start: 87354185
Gene end: 87368742
  
Corresponding Affymetrix probe sets: 10436698 (MoGene1.0st)   1430380_at (Mouse Genome 430 2.0 Array)   1453821_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113217
Ensembl peptide - ENSMUSP00000113229
Ensembl peptide - ENSMUSP00000061835
Ensembl peptide - ENSMUSP00000112510
NCBI entrez gene - 67768     See in Manteia.
MGI - MGI:1915018
RefSeq - NM_001159331
RefSeq - NM_026366
RefSeq Peptide - NP_001152803
RefSeq Peptide - NP_080642
swissprot - Q6SKR2
swissprot - D3Z6J0
swissprot - Q6PRU9
swissprot - E9PXT7
Ensembl - ENSMUSG00000044442
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 n6amt1ENSDARG00000115421Danio rerio
 N6AMT1ENSGALG00000015802Gallus gallus
 N6AMT1ENSG00000156239Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002052  DNA methylase, N-6 adenine-specific, conserved site
 IPR004557  Eukaryotic/archaeal PrmC-related
 IPR007848  Methyltransferase small domain
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006479 protein methylation IEA
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008276 protein methyltransferase activity ISO
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Methylation
Eukaryotic Translation Termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Col4a2ENU4020/Col4a2+
Genetic Background: C3.D2-Col4a2ENU4020

 MP:0001693 failure of primitive streak formation "inability to form the epiblast ridge from which arises the germ layers of the embryo" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:33880]
Show

Allelic Composition: Col4a2ENU4020/Col4a2+
Genetic Background: C3.D2-Col4a2ENU4020

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Col4a2ENU4020/Col4a2+
Genetic Background: C3.D2-Col4a2ENU4020

 MP:0004965 inner cell mass degeneration 
Show

Allelic Composition: Col4a2ENU4020/Col4a2+
Genetic Background: C3.D2-Col4a2ENU4020

 MP:0005032 abnormal ectoplacental cone 
Show

Allelic Composition: Col4a2ENU4020/Col4a2+
Genetic Background: C3.D2-Col4a2ENU4020

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Col4a2ENU4020/Col4a2+
Genetic Background: C3.D2-Col4a2ENU4020

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024360 Etf1 / Q8BWY3 / Eukaryotic peptide chain release factor subunit 1 / P62495* / eukaryotic translation termination factor 1*  / reaction
 ENSMUSG00000071723 Gspt2 / Q149F3 / G1 to S phase transition 2 / Q8IYD1*  / reaction
 ENSMUSG00000062203 Gspt1 / Q8R050 / G1 to S phase transition 1 / P15170*  / reaction
 ENSMUSG00000038812 Q9DCG9 / Trmt112 / tRNA methyltransferase 11-2 / Q9UI30* / tRNA methyltransferase subunit 11-2*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr