ENSG00000156239


Homo sapiens

Features
Gene ID: ENSG00000156239
  
Biological name :N6AMT1
  
Synonyms : N-6 adenine-specific DNA methyltransferase 1 / N6AMT1 / Q9Y5N5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q21.3
Gene start: 28872191
Gene end: 28885371
  
Corresponding Affymetrix probe sets: 220311_at (Human Genome U133 Plus 2.0 Array)   234676_s_at (Human Genome U133 Plus 2.0 Array)   234698_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000286764
Ensembl peptide - ENSP00000303584
Ensembl peptide - ENSP00000436490
NCBI entrez gene - 29104     See in Manteia.
OMIM - 614553
RefSeq - NM_013240
RefSeq - NM_182749
RefSeq Peptide - NP_037372
RefSeq Peptide - NP_877426
swissprot - Q9Y5N5
Ensembl - ENSG00000156239
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 n6amt1ENSDARG00000115421Danio rerio
 N6AMT1ENSGALG00000015802Gallus gallus
 N6amt1ENSMUSG00000044442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002052  DNA methylase, N-6 adenine-specific, conserved site
 IPR004557  Eukaryotic/archaeal PrmC-related
 IPR007848  Methyltransferase small domain
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006415 translational termination TAS
 biological_processGO:0006479 protein methylation IEA
 biological_processGO:0030307 positive regulation of cell growth IDA
 biological_processGO:0032259 methylation TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008276 protein methyltransferase activity IDA
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Methylation
Eukaryotic Translation Termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000103342 GSPT1 / P15170 / G1 to S phase transition 1  / reaction
 ENSG00000120705 ETF1 / P62495 / eukaryotic translation termination factor 1  / reaction
 ENSG00000189369 GSPT2 / Q8IYD1 / G1 to S phase transition 2  / reaction
 ENSG00000173113 Q9UI30 / TRMT112 / tRNA methyltransferase subunit 11-2  / complex






 

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