ENSMUSG00000045078


Mus musculus

Features
Gene ID: ENSMUSG00000045078
  
Biological name :Rnf216
  
Synonyms : E3 ubiquitin-protein ligase RNF216 / P58283 / Rnf216
  
Possible biological names infered from orthology : Q9NWF9 / ring finger protein 216
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G2
Gene start: 142990893
Gene end: 143112994
  
Corresponding Affymetrix probe sets: 10535389 (MoGene1.0st)   1437532_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143705
Ensembl peptide - ENSMUSP00000052563
Ensembl peptide - ENSMUSP00000142355
Ensembl peptide - ENSMUSP00000143242
NCBI entrez gene - 108086     See in Manteia.
MGI - MGI:1344349
RefSeq - XM_017320593
RefSeq - XM_006504646
RefSeq - XM_006504648
RefSeq - XM_011240968
RefSeq - XM_017320591
RefSeq - XM_017320592
RefSeq - NM_080561
RefSeq - NM_207110
RefSeq - XM_006504644
RefSeq - XM_006504645
RefSeq Peptide - NP_542128
RefSeq Peptide - NP_996993
swissprot - A0A0G2JFN3
swissprot - P58283
swissprot - A0A0G2JDG1
Ensembl - ENSMUSG00000045078
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf216ENSDARG00000087893Danio rerio
 RNF216ENSGALG00000004629Gallus gallus
 Q9NWF9ENSG00000011275Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002867  IBR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032648 regulation of interferon-beta production IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0050691 regulation of defense response to virus by host IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000220 increased monocyte count "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0005016 decreased lymphocyte number "fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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