ENSMUSG00000045364


Mus musculus

Features
Gene ID: ENSMUSG00000045364
  
Biological name :Ifne
  
Synonyms : Ifne / Interferon epsilon / Q80ZF2
  
Possible biological names infered from orthology : Q86WN2
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: C4
Gene start: 88879538
Gene end: 88880201
  
Corresponding Affymetrix probe sets: 10514335 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000059199
NCBI entrez gene - 230405     See in Manteia.
MGI - MGI:2667156
RefSeq - NM_177348
RefSeq Peptide - NP_796322
swissprot - Q80ZF2
Ensembl - ENSMUSG00000045364
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IFNEENSG00000184995Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ifnb1 / P01575 / interferon beta 1, fibroblast / P01574* / interferon beta 1*ENSMUSG0000004880622


Protein motifs (from Interpro)
Interpro ID Name
 IPR000471  Interferon alpha/beta/delta
 IPR009079  Four-helical cytokine-like, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IBA
 biological_processGO:0002286 T cell activation involved in immune response IBA
 biological_processGO:0002323 natural killer cell activation involved in immune response IBA
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006959 humoral immune response IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0030183 B cell differentiation IBA
 biological_processGO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein IBA
 biological_processGO:0042100 B cell proliferation IBA
 biological_processGO:0042742 defense response to bacterium IMP
 biological_processGO:0043330 response to exogenous dsRNA IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0051607 defense response to virus IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005126 cytokine receptor binding IEA
 molecular_functionGO:0005132 type I interferon receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001212 skin lesions "focal patches of inflammation on the skin" [J:30162]
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Allelic Composition: Nek8tm1Bei/Nek8jck
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nek8tm1Bei/Nek8jck
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr

 MP:0002418 increased susceptibility to viral infection "greater likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nek8tm1Bei/Nek8jck
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr

 MP:0008045 decreased NK cell number "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
Show

Allelic Composition: Nek8tm1Bei/Nek8jck
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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