ENSMUSG00000045482


Mus musculus

Features
Gene ID: ENSMUSG00000045482
  
Biological name :Trrap
  
Synonyms : transformation/transcription domain associated protein / Trrap
  
Possible biological names infered from orthology : Q9Y4A5
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 144767732
Gene end: 144859778
  
Corresponding Affymetrix probe sets: 10527340 (MoGene1.0st)   10527423 (MoGene1.0st)   1416532_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000091668
Ensembl peptide - ENSMUSP00000042544
Ensembl peptide - ENSMUSP00000098035
Ensembl peptide - ENSMUSP00000148419
Ensembl peptide - ENSMUSP00000122021
Ensembl peptide - ENSMUSP00000115917
NCBI entrez gene - 100683     See in Manteia.
MGI - MGI:2153272
RefSeq - XM_017320578
RefSeq - XM_006504793
RefSeq - XM_006504794
RefSeq - XM_006504795
RefSeq - XM_011240999
RefSeq - XM_017320575
RefSeq - XM_017320576
RefSeq - XM_017320577
RefSeq - NM_001081362
RefSeq - XM_006504781
RefSeq - XM_006504782
RefSeq - XM_006504783
RefSeq - XM_006504784
RefSeq - XM_006504785
RefSeq - XM_006504786
RefSeq - XM_006504787
RefSeq - XM_006504788
RefSeq - XM_006504789
RefSeq - XM_006504790
RefSeq - XM_006504792
RefSeq Peptide - NP_001074831
swissprot - E9PZA7
swissprot - E9PWT1
swissprot - E9QLK7
swissprot - D3YY11
swissprot - A0A1D5RLL4
swissprot - F7CGG2
Ensembl - ENSMUSG00000045482
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trrapENSDARG00000100623Danio rerio
 TRRAPENSGALG00000003596Gallus gallus
 TRRAPENSG00000196367Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000403  Phosphatidylinositol 3-/4-kinase, catalytic domain
 IPR003151  PIK-related kinase, FAT
 IPR003152  FATC domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR014009  PIK-related kinase
 IPR016024  Armadillo-type fold
 IPR033317  Transcription-associated protein 1
 IPR036940  Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0016578 histone deubiquitination IEA
 biological_processGO:0043967 histone H4 acetylation IEA
 biological_processGO:0043968 histone H2A acetylation IEA
 biological_processGO:1903506 regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0000123 histone acetyltransferase complex IEA
 cellular_componentGO:0000812 Swr1 complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0030914 STAGA complex IEA
 cellular_componentGO:0033276 transcription factor TFTC complex IEA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IEA
 molecular_functionGO:0003712 transcription coregulator activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Formation of the beta-catenin:TCF transactivating complex
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+,Pafah1b2Gt(Betageo)1Cla/Pafah1b2Gt(Betageo)1Cla,Pafah1b3tm1Cla/Pafah1b3tm1Cla
Genetic Background: involves: 129S6/SvEvTac

 MP:0002086 abnormal extraembryonic tissue morphology "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+,Pafah1b2Gt(Betageo)1Cla/Pafah1b2Gt(Betageo)1Cla,Pafah1b3tm1Cla/Pafah1b3tm1Cla
Genetic Background: involves: 129S6/SvEvTac

 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0004964 absent inner cell mass "absence of the cells of the blastocyst that develop into the body of the embryo" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+,Pafah1b2Gt(Betageo)1Cla/Pafah1b2Gt(Betageo)1Cla,Pafah1b3tm1Cla/Pafah1b3tm1Cla
Genetic Background: involves: 129S6/SvEvTac

 MP:0005031 abnormal trophoblast "malformation of the mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+,Pafah1b2Gt(Betageo)1Cla/Pafah1b2Gt(Betageo)1Cla,Pafah1b3tm1Cla/Pafah1b3tm1Cla
Genetic Background: involves: 129S6/SvEvTac

 MP:0005033 abnormal trophoblast cells "anomaly of the cells covering the blastocyst that erode the uterine mucosa and contribute to the formation of the placenta " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+,Pafah1b2Gt(Betageo)1Cla/Pafah1b2Gt(Betageo)1Cla,Pafah1b3tm1Cla/Pafah1b3tm1Cla
Genetic Background: involves: 129S6/SvEvTac

 MP:0010092 increased circulating magnesium level "an elevation in the blood concentration of magnesium" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Gsk3btm1Jrw/Gsk3b+,Runx2tm1Kish/Runx2+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+,Pafah1b2Gt(Betageo)1Cla/Pafah1b2Gt(Betageo)1Cla,Pafah1b3tm1Cla/Pafah1b3tm1Cla
Genetic Background: involves: 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr