ENSG00000196367


Homo sapiens

Features
Gene ID: ENSG00000196367
  
Biological name :TRRAP
  
Synonyms : Q9Y4A5 / transformation/transcription domain associated protein / TRRAP
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 98877933
Gene end: 99050831
  
Corresponding Affymetrix probe sets: 1559426_at (Human Genome U133 Plus 2.0 Array)   202642_s_at (Human Genome U133 Plus 2.0 Array)   214908_s_at (Human Genome U133 Plus 2.0 Array)   220687_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000403708
Ensembl peptide - ENSP00000485781
Ensembl peptide - ENSP00000496512
Ensembl peptide - ENSP00000347733
Ensembl peptide - ENSP00000352925
Ensembl peptide - ENSP00000394645
Ensembl peptide - ENSP00000401107
NCBI entrez gene - 8295     See in Manteia.
OMIM - 603015
RefSeq - NM_003496
RefSeq - NM_001244580
RefSeq Peptide - NP_001231509
RefSeq Peptide - NP_003487
swissprot - Q9Y4A5
swissprot - F2Z2U4
swissprot - H0Y4W2
swissprot - C9K0N1
Ensembl - ENSG00000196367
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trrapENSDARG00000100623Danio rerio
 TRRAPENSGALG00000003596Gallus gallus
 TrrapENSMUSG00000045482Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000403  Phosphatidylinositol 3-/4-kinase, catalytic domain
 IPR003151  PIK-related kinase, FAT
 IPR003152  FATC domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR014009  PIK-related kinase
 IPR016024  Armadillo-type fold
 IPR033317  Transcription-associated protein 1
 IPR036940  Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0016578 histone deubiquitination IDA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0043967 histone H4 acetylation IDA
 biological_processGO:0043968 histone H2A acetylation IDA
 biological_processGO:1904837 beta-catenin-TCF complex assembly TAS
 cellular_componentGO:0000123 histone acetyltransferase complex IEA
 cellular_componentGO:0000125 PCAF complex NAS
 cellular_componentGO:0000812 Swr1 complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0030914 STAGA complex IDA
 cellular_componentGO:0033276 transcription factor TFTC complex IDA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IDA
 molecular_functionGO:0003712 transcription coregulator activity IDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity TAS


Pathways (from Reactome)
Pathway description
Formation of the beta-catenin:TCF transactivating complex
HATs acetylate histones
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000138795 LEF1 / Q9UJU2 / lymphoid enhancer binding factor 1  / reaction / complex
 ENSG00000148737 Q9NQB0 / TCF7L2 / transcription factor 7 like 2  / complex / reaction
 ENSG00000175792 Q9Y265 / RUVBL1 / RuvB like AAA ATPase 1  / reaction / complex
 ENSG00000172977 KAT5 / Q92993 / lysine acetyltransferase 5  / reaction / complex
 ENSG00000276180 P62805 / HIST1H4I / histone cluster 1 H4 family member i  / reaction
 ENSG00000168148 Q16695 / HIST3H3 / histone cluster 3 H3  / reaction
 ENSG00000168036 CTNNB1 / P35222 / catenin beta 1  / complex / reaction






 

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