ENSMUSG00000045502


Mus musculus

Features
Gene ID: ENSMUSG00000045502
  
Biological name :Hcar2
  
Synonyms : Hcar2 / Hydroxycarboxylic acid receptor 2 / Q9EP66
  
Possible biological names infered from orthology : HCAR3 / hydroxycarboxylic acid receptor 3 / P49019 / Q8TDS4
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 123863570
Gene end: 123865499
  
Corresponding Affymetrix probe sets: 10533720 (MoGene1.0st)   1419721_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000054104
NCBI entrez gene - 80885     See in Manteia.
MGI - MGI:1933383
RefSeq - NM_030701
RefSeq Peptide - NP_109626
swissprot - Q0VBA6
swissprot - Q9EP66
Ensembl - ENSMUSG00000045502
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HCAR2ENSG00000182782Homo sapiens
 HCAR3ENSG00000255398Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hcar1 / hydroxycarboxylic acid receptor 1 / Q9BXC0*ENSMUSG0000004924149
Gpr31b / F8VQN3 / 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor / GPR31* / O00270* / G protein-coupled receptor 31*ENSMUSG0000007131130


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR028017  Hydroxycarboxylic acid receptor 2/3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001781 neutrophil apoptotic process ISO
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0033031 positive regulation of neutrophil apoptotic process ISS
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0050995 negative regulation of lipid catabolic process IEA
 biological_processGO:0070165 positive regulation of adiponectin secretion ISS
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0030054 cell junction ISO
 molecular_functionGO:0001614 purinergic nucleotide receptor activity IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005525 GTP binding IDA
 molecular_functionGO:0070553 nicotinic acid receptor activity ISS


Pathways (from Reactome)
Pathway description
Hydroxycarboxylic acid-binding receptors
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002118 abnormal lipid homeostasis "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ndntm1Alb/Ndn+
Genetic Background: involves: 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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