ENSMUSG00000049241


Mus musculus

Features
Gene ID: ENSMUSG00000049241
  
Biological name :Hcar1
  
Synonyms : Hcar1 / hydroxycarboxylic acid receptor 1
  
Possible biological names infered from orthology : Q9BXC0
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 123876736
Gene end: 123880020
  
Corresponding Affymetrix probe sets: 10533725 (MoGene1.0st)   1438411_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000129280
NCBI entrez gene - 243270     See in Manteia.
MGI - MGI:2441671
RefSeq - NM_175520
RefSeq Peptide - NP_780729
swissprot - E9PZR8
Ensembl - ENSMUSG00000049241
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HCAR1ENSG00000196917Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hcar2 / Q9EP66 / Hydroxycarboxylic acid receptor 2 / HCAR3* / P49019* / Q8TDS4* / hydroxycarboxylic acid receptor 3*ENSMUSG0000004550250
Gpr31b / F8VQN3 / 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor / GPR31* / O00270* / G protein-coupled receptor 31*ENSMUSG0000007131128


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR028016  Hydroxycarboxylic acid receptor 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
Hydroxycarboxylic acid-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008033 impaired lipolysis "reduction in the rate of the hydrolysis of fat into free fatty acids " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Stat6tm1Gru/Stat6tm1Gru,Tg(Scgb1a1-Il13)2Eli/?,Tg(Scgb1a1-STAT6)1Erle/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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