ENSMUSG00000045659


Mus musculus

Features
Gene ID: ENSMUSG00000045659
  
Biological name :Plekha7
  
Synonyms : Pleckstrin homology domain-containing family A member 7 / Plekha7 / Q3UIL6
  
Possible biological names infered from orthology : pleckstrin homology domain containing A7 / Q6IQ23
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F1
Gene start: 116123485
Gene end: 116308376
  
Corresponding Affymetrix probe sets: 10567134 (MoGene1.0st)   1434889_at (Mouse Genome 430 2.0 Array)   1439229_at (Mouse Genome 430 2.0 Array)   1455343_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145800
Ensembl peptide - ENSMUSP00000138766
Ensembl peptide - ENSMUSP00000145894
Ensembl peptide - ENSMUSP00000151060
Ensembl peptide - ENSMUSP00000150646
Ensembl peptide - ENSMUSP00000148936
Ensembl peptide - ENSMUSP00000081714
Ensembl peptide - ENSMUSP00000138126
Ensembl peptide - ENSMUSP00000138214
Ensembl peptide - ENSMUSP00000138257
Ensembl peptide - ENSMUSP00000138490
Ensembl peptide - ENSMUSP00000138544
Ensembl peptide - ENSMUSP00000138575
NCBI entrez gene - 233765     See in Manteia.
MGI - MGI:2445094
RefSeq - XM_017322198
RefSeq - XM_017322185
RefSeq - XM_017322186
RefSeq - XM_017322187
RefSeq - XM_017322188
RefSeq - XM_017322189
RefSeq - XM_017322190
RefSeq - XM_017322191
RefSeq - XM_017322192
RefSeq - XM_017322193
RefSeq - XM_017322194
RefSeq - XM_017322195
RefSeq - XM_017322196
RefSeq - XM_017322197
RefSeq - NM_001305185
RefSeq - NM_001305186
RefSeq - NM_001305189
RefSeq - NM_001305190
RefSeq - NM_172743
RefSeq Peptide - NP_766331
RefSeq Peptide - NP_001292114
RefSeq Peptide - NP_001292115
RefSeq Peptide - NP_001292118
RefSeq Peptide - NP_001292119
swissprot - A0A1L1SV63
swissprot - S4R243
swissprot - A0A0U1RP25
swissprot - S4R190
swissprot - A0A1L1SU82
swissprot - A0A1L1SQ79
swissprot - A0A0U1RPA0
swissprot - Q3UIL6
Ensembl - ENSMUSG00000045659
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plekha7aENSDARG00000060813Danio rerio
 plekha7bENSDARG00000062220Danio rerio
 PLEKHA7ENSGALG00000029679Gallus gallus
 Q6IQ23ENSG00000166689Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plekha5 / pleckstrin homology domain containing A5 / Q9HAU0*ENSMUSG0000003023132
Q7TQG1 / Plekha6 / Pleckstrin homology domain-containing family A member 6 / Q9Y2H5* / pleckstrin homology domain containing A6*ENSMUSG0000004175727
Plekha4 / pleckstrin homology domain containing A4 / Q9H4M7*ENSMUSG0000004042820


Protein motifs (from Interpro)
Interpro ID Name
 IPR001202  WW domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR036020  WW domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045218 zonula adherens maintenance ISO
 biological_processGO:0090136 epithelial cell-cell adhesion ISS
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005915 zonula adherens ISO
 cellular_componentGO:0030054 cell junction ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0070097 delta-catenin binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002411 decreased susceptibility to bacterial infection "reduced likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gfi1tm1(cre)Gan/Gfi1+,Rfx1tm1.1Wrth/Rfx1tm1.1Wrth,Rfx3tm2Wrth/Rfx3tm2Wrth
Genetic Background: involves: 129 * 129S7/SvEvBrd

 MP:0009789 decreased susceptibility to bacterial infection induced morbidity/mortality "reduced likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gfi1tm1(cre)Gan/Gfi1+,Rfx1tm1.1Wrth/Rfx1tm1.1Wrth,Rfx3tm2Wrth/Rfx3tm2Wrth
Genetic Background: involves: 129 * 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr