ENSMUSG00000046185


Mus musculus

Features
Gene ID: ENSMUSG00000046185
  
Biological name :Zfp84
  
Synonyms : Zfp84 / zinc finger protein 84
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B1
Gene start: 29768552
Gene end: 29779821
  
Corresponding Affymetrix probe sets: 10551760 (MoGene1.0st)   1425209_at (Mouse Genome 430 2.0 Array)   1425210_s_at (Mouse Genome 430 2.0 Array)   1435916_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032802
NCBI entrez gene - 74352     See in Manteia.
MGI - MGI:107780
RefSeq - NM_023750
RefSeq Peptide - NP_076239
swissprot - Q9D654
Ensembl - ENSMUSG00000046185
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3V080 / Zfp583 / zinc finger protein 583 / Q96ND8* / ZNF583*ENSMUSG0000003044343
Zfp82 / Q6P9Y7 / zinc finger protein 82 / Q8N141* / ZFP82 zinc finger protein*ENSMUSG0000009802243
Zfp790 / zinc finger protein 790 / Q6PG37* / ZNF790*ENSMUSG0000001142742
Zfp30 / zinc finger protein 30 / Q9Y2G7* / ZFP30 zinc finger protein*ENSMUSG0000004747342
Zfp383 / zinc finger protein 383 / Q8NA42* / ZNF383*ENSMUSG0000009968942
Zfp454 / zinc finger protein 454 / Q8N9F8* / ZNF454*ENSMUSG0000004872842
Zfp14 / P10755 / zinc finger protein 14 / Q9HCL3* / ZFP14 zinc finger protein*ENSMUSG0000005398542
Zfp28 / P10078 / zinc finger protein 28 / Q8NHY6* / ZFP28 zinc finger protein*ENSMUSG0000006286141
Zfp568 / E9PYI1 / zinc finger protein 568 / ZNF571* / Q7Z3V5* / zinc finger protein 571*ENSMUSG0000007422140
Zfp78 / zinc finger protein 78 / Q9BX82* / ZNF471* / zinc finger protein 471*ENSMUSG0000005515039
Zfp940 / zinc finger protein 940 / Q6PG37* / ZNF790* / zinc finger protein 790*ENSMUSG0000005085539
Gm3854 / Q96NG8* / ZNF582* / zinc finger protein 582*ENSMUSG0000010939839
Zfp566 / zinc finger protein 566 / Q969W8* / ZNF566*ENSMUSG0000007876832


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000220 increased monocyte count "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0005018 decreased T cell number "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0008075 decreased CD4-positive T cell number "reduced number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0008079 decreased CD8-positive T cell number "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0010169 decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number "a reduction in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]
Show

Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0010845 decreased effector memory CD4-positive, alpha-beta T cell number "reduced number of CD4-positive, alpha-beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative" [CL:0000905, GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm]
Show

Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

 MP:0012765 decreased alpha-beta T cell number "reduced number of T cells that expresses an alpha-beta T cell receptor complex" [CL:0000789]
Show

Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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