ENSMUSG00000046623


Mus musculus

Features
Gene ID: ENSMUSG00000046623
  
Biological name :Gjb4
  
Synonyms : gap junction protein, beta 4 / Gjb4 / Q02738
  
Possible biological names infered from orthology : Q9NTQ9
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D2.2
Gene start: 127351086
Gene end: 127354081
  
Corresponding Affymetrix probe sets: 10516487 (MoGene1.0st)   1422179_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053307
Ensembl peptide - ENSMUSP00000101696
NCBI entrez gene - 14621     See in Manteia.
MGI - MGI:95722
RefSeq - NM_008127
RefSeq Peptide - NP_032153
swissprot - Q02738
Ensembl - ENSMUSG00000046623
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cx34.4ENSDARG00000075854Danio rerio
 GJB4ENSG00000189433Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gjb5 / Q02739 / gap junction protein, beta 5 / O95377*ENSMUSG0000004235759
Gjb3 / P28231 / gap junction protein, beta 3 / O75712*ENSMUSG0000004236757
Gjb6 / P70689 / gap junction protein, beta 6 / O95452*ENSMUSG0000004005544
Gjb2 / Q00977 / gap junction protein, beta 2 / P29033*ENSMUSG0000004635244
Gjb1 / P28230 / gap junction protein, beta 1 / P08034*ENSMUSG0000004779744
Gjd4 / Q8BSD4 / gap junction protein, delta 4 / Q96KN9*ENSMUSG0000003685527
Gjc3 / Q921C1 / gap junction protein, gamma 3 / Q8NFK1*ENSMUSG0000005696625


Protein motifs (from Interpro)
Interpro ID Name
 IPR000500  Connexin
 IPR002270  Gap junction beta-4 protein (Cx31.1)
 IPR013092  Connexin, N-terminal
 IPR017990  Connexin, conserved site
 IPR019570  Gap junction protein, cysteine-rich domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0007608 sensory perception of smell IMP
 biological_processGO:0042048 olfactory behavior IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0005922 connexin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction ISO


Pathways (from Reactome)
Pathway description
Gap junction assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008544 impaired olfaction "reduced ability to detect odors" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Apctm3Mmt/Apc+
Genetic Background: involves: 129X1/SvJ * C57BL/6N

 MP:0009709 hydrometra "an accumulation in the uterine lumen of normal secretions that ordinarily drain from the body but are retained when the cervix or vagina is significantly or completely closed" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Folh1tm1b(KOMP)Wtsi/Folh1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Folh1tm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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