ENSMUSG00000046785


Mus musculus

Features
Gene ID: ENSMUSG00000046785
  
Biological name :Epm2aip1
  
Synonyms : EPM2A-interacting protein 1 / Epm2aip1 / Q8VEH5
  
Possible biological names infered from orthology : Q7L775
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F3
Gene start: 111271929
Gene end: 111279093
  
Corresponding Affymetrix probe sets: 10589756 (MoGene1.0st)   1425624_at (Mouse Genome 430 2.0 Array)   1434105_at (Mouse Genome 430 2.0 Array)   1434106_at (Mouse Genome 430 2.0 Array)   1454835_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052904
Ensembl peptide - ENSMUSP00000120245
NCBI entrez gene - 77781     See in Manteia.
MGI - MGI:1925031
RefSeq - NM_175266
RefSeq Peptide - NP_780475
swissprot - Q8VEH5
Ensembl - ENSMUSG00000046785
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q7L775ENSG00000178567Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q99NI3 / Gtf2ird2 / ral transcription factor II-I repeat domain-containing protein 2 / Q6EKJ0* / Q86UP8* / GTF2IRD2B* / GTF2I repeat domain containing 2* / GTF2I repeat domain containing 2B*ENSMUSG0000001594223
Zbed5 / zinc finger, BED type containing 5 / ZBED8* / Q8IZ13* / zinc finger BED-type containing 8*ENSMUSG0000003417319


Protein motifs (from Interpro)
Interpro ID Name
 IPR026630  EPM2A-interacting protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0032868 response to insulin IMP
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process IMP
 biological_processGO:2000467 positive regulation of glycogen (starch) synthase activity IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Hmgb1tm1.1Ttg/Hmgb1tm1.2Ttg,Tg(CAG-cre)13Miya/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hmgb1tm1.1Ttg/Hmgb1tm1.2Ttg,Tg(CAG-cre)13Miya/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Hmgb1tm1.1Ttg/Hmgb1tm1.2Ttg,Tg(CAG-cre)13Miya/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003213 resistance to age related obesity "reduced probability of excessive weight gain that is progressive with age" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Hmgb1tm1.1Ttg/Hmgb1tm1.2Ttg,Tg(CAG-cre)13Miya/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003383 abnormal gluconeogenesis "anomaly in the formation of glucose from noncarbohydrates, such as proteins or fat" [J:93896]
Show

Allelic Composition: Hmgb1tm1.1Ttg/Hmgb1tm1.2Ttg,Tg(CAG-cre)13Miya/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Hmgb1tm1.1Ttg/Hmgb1tm1.2Ttg,Tg(CAG-cre)13Miya/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005438 abnormal glycogen homeostasis "abnormal processing and or utilization of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Hmgb1tm1.1Ttg/Hmgb1tm1.2Ttg,Tg(CAG-cre)13Miya/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hmgb1tm1.1Ttg/Hmgb1tm1.2Ttg,Tg(CAG-cre)13Miya/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010398 decreased liver glycogen level "less than the normal concentration of a readily converted carbohydrate reserve in liver" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hmgb1tm1.1Ttg/Hmgb1tm1.2Ttg,Tg(CAG-cre)13Miya/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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