ENSMUSG00000047777


Mus musculus

Features
Gene ID: ENSMUSG00000047777
  
Biological name :Phf13
  
Synonyms : PHD finger protein 13 / Phf13 / Q8K2W6
  
Possible biological names infered from orthology : Q86YI8
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E2
Gene start: 151989633
Gene end: 151996258
  
Corresponding Affymetrix probe sets: 10518847 (MoGene1.0st)   1455175_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062590
NCBI entrez gene - 230936     See in Manteia.
MGI - MGI:2446217
RefSeq - NM_172705
RefSeq Peptide - NP_766293
swissprot - Q3V230
swissprot - Q8K2W6
Ensembl - ENSMUSG00000047777
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phf13ENSDARG00000102023Danio rerio
 PHF13ENSGALG00000028148Gallus gallus
 PHF13ENSG00000116273Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Phf23 / Q8BSN5 / PHD finger protein 23 / Q9BUL5*ENSMUSG0000001857236


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019787  Zinc finger, PHD-finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007076 mitotic chromosome condensation ISS
 biological_processGO:0030261 chromosome condensation IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001145 abnormal male reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Phf13Gt(XB691)Byg/Phf13Gt(XB691)Byg
Genetic Background: B6.129P2-Phf13Gt(XB691)Byg

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

Allelic Composition: Phf13Gt(XB691)Byg/Phf13Gt(XB691)Byg
Genetic Background: B6.129P2-Phf13Gt(XB691)Byg

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0003205 testicular atrophy "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Phf13Gt(XB691)Byg/Phf13Gt(XB691)Byg
Genetic Background: B6.129P2-Phf13Gt(XB691)Byg

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0010769 abnormal survival "deviation from the expected viability or life span of an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Phf13Gt(XB691)Byg/Phf13Gt(XB691)Byg
Genetic Background: B6.129P2-Phf13Gt(XB691)Byg

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Inpp5btm1Nbm/Inpp5btm1Nbm,Ocrltm1Nbm/Y,Tg(INPP5B)CNbm/Tg(INPP5B)CNbm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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