ENSMUSG00000049038


Mus musculus

Features
Gene ID: ENSMUSG00000049038
  
Biological name :Mterf2
  
Synonyms : Mterf2 / Q8BKY8 / Transcription termination factor 2, mitochondrial
  
Possible biological names infered from orthology : mitochondrial transcription termination factor 2 / Q49AM1
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 85119433
Gene end: 85128027
  
Corresponding Affymetrix probe sets: 10371396 (MoGene1.0st)   1455700_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062762
Ensembl peptide - ENSMUSP00000150772
Ensembl peptide - ENSMUSP00000150699
Ensembl peptide - ENSMUSP00000150091
NCBI entrez gene - 74238     See in Manteia.
MGI - MGI:1921488
RefSeq - XM_006514248
RefSeq - NM_028832
RefSeq - XM_006514247
RefSeq Peptide - NP_083108
swissprot - A0A1L1SUH9
swissprot - Q8BKY8
swissprot - A0A1L1SSZ1
swissprot - A0A1L1SUB1
Ensembl - ENSMUSG00000049038
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mterf2ENSDARG00000086405Danio rerio
 MTERF2ENSGALG00000012639Gallus gallus
 MTERF2ENSG00000120832Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mterf1b / MTERF1* / Q99551* / mitochondrial transcription termination factor 1*ENSMUSG0000005317823
Q8CHZ9 / Mterf1a / Transcription termination factor 1a, mitochondrial / MTERF1* / Q99551* / mitochondrial transcription termination factor 1*ENSMUSG0000004042923


Protein motifs (from Interpro)
Interpro ID Name
 IPR003690  Transcription termination factor, mitochondrial/chloroplastic


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006393 termination of mitochondrial transcription IBA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0042645 mitochondrial nucleoid IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000747 muscle weakness "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

 MP:0008414 abnormal spatial reference memory "anomaly in the ability to recall spatial location information from previous encounters or training sessions in order to naviagate or perform other behavior using such locational cues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

 MP:0010954 abnormal cellular respiration "anomaly in the enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)" [GO:0045333]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

 MP:0010956 abnormal mitochondrial ATP synthesis coupled electron transport "anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

 MP:0010958 abnormal tricarboxylic acid cycle "any anomaly in the universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes; the acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle" [GO:0006099]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

 MP:0011628 increased mitochondria number "greater than normal number of the cellular organelles responsible for energy production" [MGI:csmith]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

 MP:0011630 increased mitochondria size "enlarged the cellular organelles responsible for energy production" [MGI:csmith]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

 MP:0011638 abnormal mitochondrial chromosome morphology "any structrual anomaly of the chromosome found in the mitochondrion of a eukaryotic cell" [GO:0000262]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

 MP:0012106 impaired exercise endurance "impaired performance during controlled physical activity" [MGI:smb]
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Allelic Composition: Arsbm1J/Arsbm1J
Genetic Background: C57BL/6J-Arsbm1J/GrsrJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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