ENSMUSG00000049580


Mus musculus

Features
Gene ID: ENSMUSG00000049580
  
Biological name :Tsku
  
Synonyms : Q8CBR6 / Tsku / tsukushi, small leucine rich proteoglycan
  
Possible biological names infered from orthology : Q8WUA8
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E1
Gene start: 98350668
Gene end: 98361328
  
Corresponding Affymetrix probe sets: 10565727 (MoGene1.0st)   1440230_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146025
Ensembl peptide - ENSMUSP00000127242
Ensembl peptide - ENSMUSP00000128431
Ensembl peptide - ENSMUSP00000130917
Ensembl peptide - ENSMUSP00000091713
Ensembl peptide - ENSMUSP00000131789
Ensembl peptide - ENSMUSP00000137437
NCBI entrez gene - 244152     See in Manteia.
MGI - MGI:2443855
RefSeq - XM_006507837
RefSeq - NM_001024619
RefSeq - NM_001168539
RefSeq - NM_001168540
RefSeq - NM_001168541
RefSeq - XM_006507832
RefSeq - XM_006507833
RefSeq - XM_006507834
RefSeq - XM_006507835
RefSeq - XM_006507836
RefSeq Peptide - NP_001019790
RefSeq Peptide - NP_001162011
RefSeq Peptide - NP_001162012
RefSeq Peptide - NP_001162013
swissprot - Q08EE6
swissprot - Q8CBR6
Ensembl - ENSMUSG00000049580
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tskuENSDARG00000040815Danio rerio
 TSKUENSGALG00000000761Gallus gallus
 TSKUENSG00000182704Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0021540 corpus callosum morphogenesis IMP
 biological_processGO:0021670 lateral ventricle development IMP
 biological_processGO:0021960 anterior commissure morphogenesis IMP
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IDA
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0061073 ciliary body morphogenesis IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005886 plasma membrane IBA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000780 abnormal corpus callosum morphology "malformation or absence of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mapk8ip2tm1.1Gol/Mapk8ip2tm1.1Gol
Genetic Background: 129S/SvEv-Mapk8ip2tm1.1Gol

 MP:0008225 abnormal anterior commissure morphology "any structural anomaly of a round bundle of nerve fibers that crosses the midline of the brain near the anterior limit of the third ventricle" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Mapk8ip2tm1.1Gol/Mapk8ip2tm1.1Gol
Genetic Background: 129S/SvEv-Mapk8ip2tm1.1Gol

 MP:0008535 enlarged lateral ventricles "increased size of the cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MESH:A08.186.211.276.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mapk8ip2tm1.1Gol/Mapk8ip2tm1.1Gol
Genetic Background: 129S/SvEv-Mapk8ip2tm1.1Gol

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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