ENSMUSG00000049882


Mus musculus

Features
Gene ID: ENSMUSG00000049882
  
Biological name :Vcpkmt
  
Synonyms : Q8C436 / valosin containing protein lysine (K) methyltransferase / Vcpkmt
  
Possible biological names infered from orthology : Q9H867 / valosin containing protein lysine methyltransferase
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: C2
Gene start: 69577628
Gene end: 69583028
  
Corresponding Affymetrix probe sets: 10400710 (MoGene1.0st)   1455726_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055002
NCBI entrez gene - 207965     See in Manteia.
MGI - MGI:2684917
RefSeq - NM_001033236
RefSeq - XM_011244052
RefSeq Peptide - NP_001028408
swissprot - Q8C436
Ensembl - ENSMUSG00000049882
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vcpkmtENSDARG00000060021Danio rerio
 VCPKMTENSGALG00000012269Gallus gallus
 Q9H867ENSG00000100483Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8CDZ2 / Mettl21e / Protein-lysine methyltransferase METTL21E ENSMUSG0000004682829
Q9CQL0 / Mettl21a / Protein N-lysine methyltransferase METTL21A / Q8WXB1* / methyltransferase like 21A*ENSMUSG0000002595629
D3YWP0 / Mettl21b / EEF1A lysine methyltransferase 3 / Q96AZ1* / EEF1AKMT3*ENSMUSG0000008011527
Q8BLU2 / Mettl21c / Protein-lysine methyltransferase METTL21C / Q5VZV1* / methyltransferase like 21C*ENSMUSG0000004734325


Protein motifs (from Interpro)
Interpro ID Name
 IPR019410  Lysine methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018022 peptidyl-lysine methylation IEA
 biological_processGO:0018023 peptidyl-lysine trimethylation IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0032780 negative regulation of ATPase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016279 protein-lysine N-methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0051117 ATPase binding IEA


Pathways (from Reactome)
Pathway description
Protein methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Prkag2tm1.1Geno/Prkag2tm1.1Geno,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: B6.Cg-Prkag2tm1.1Geno Edil3Tg(Sox2-cre)1Amc

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028452 Vcp / Q01853 / valosin containing protein / P55072*  / reaction






 

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