ENSMUSG00000028452


Mus musculus

Features
Gene ID: ENSMUSG00000028452
  
Biological name :Vcp
  
Synonyms : Q01853 / valosin containing protein / Vcp
  
Possible biological names infered from orthology : P55072
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A5
Gene start: 42979963
Gene end: 43000507
  
Corresponding Affymetrix probe sets: 10512391 (MoGene1.0st)   1423030_at (Mouse Genome 430 2.0 Array)   1457588_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030164
NCBI entrez gene - 269523     See in Manteia.
MGI - MGI:99919
RefSeq - NM_009503
RefSeq Peptide - NP_033529
swissprot - Q01853
Ensembl - ENSMUSG00000028452
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vcpENSDARG00000020008Danio rerio
 VCPENSGALG00000001986Gallus gallus
 VCPENSG00000165280Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003338  CDC48, N-terminal subdomain
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR003960  ATPase, AAA-type, conserved site
 IPR004201  CDC48, domain 2
 IPR005938  AAA ATPase, CDC48 family
 IPR009010  Aspartate decarboxylase-like domain superfamily
 IPR015415  Vps4 oligomerisation, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029067  CDC48 domain 2-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006302 double-strand break repair IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IGI
 biological_processGO:0006734 NADH metabolic process IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0006914 autophagy ISO
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0010498 proteasomal protein catabolic process IEA
 biological_processGO:0010918 positive regulation of mitochondrial membrane potential IMP
 biological_processGO:0016236 macroautophagy IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0018279 protein N-linked glycosylation via asparagine IEA
 biological_processGO:0019079 viral genome replication IEA
 biological_processGO:0019985 translesion synthesis IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0030970 retrograde protein transport, ER to cytosol IEA
 biological_processGO:0031334 positive regulation of protein complex assembly IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0032510 endosome to lysosome transport via multivesicular body sorting pathway IEA
 biological_processGO:0034214 protein hexamerization IMP
 biological_processGO:0036503 ERAD pathway IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0046034 ATP metabolic process IDA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0061857 endoplasmic reticulum stress-induced pre-emptive quality control IEA
 biological_processGO:0070842 aggresome assembly IGI
 biological_processGO:0071712 ER-associated misfolded protein catabolic process IEA
 biological_processGO:0072389 flavin adenine dinucleotide catabolic process IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0097352 autophagosome maturation IEA
 biological_processGO:1903006 positive regulation of protein K63-linked deubiquitination IEA
 biological_processGO:1903007 positive regulation of Lys63-specific deubiquitinase activity IEA
 biological_processGO:1903715 regulation of aerobic respiration IEA
 biological_processGO:1903862 positive regulation of oxidative phosphorylation IEA
 biological_processGO:2000158 positive regulation of ubiquitin-specific protease activity IEA
 biological_processGO:2001171 positive regulation of ATP biosynthetic process IEA
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0034098 VCP-NPL4-UFD1 AAA ATPase complex IEA
 cellular_componentGO:0035861 site of double-strand break IEA
 cellular_componentGO:0036513 Derlin-1 retrotranslocation complex IDA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:1904949 ATPase complex IMP
 cellular_componentGO:1990730 VCP-NSFL1C complex IPI
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0035800 deubiquitinase activator activity IEA
 molecular_functionGO:0036435 K48-linked polyubiquitin modification-dependent protein binding IDA
 molecular_functionGO:0042288 MHC class I protein binding IDA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043531 ADP binding IMP
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding IEA
 molecular_functionGO:1904288 BAT3 complex binding IEA
 molecular_functionGO:1990381 ubiquitin-specific protease binding IPI


Pathways (from Reactome)
Pathway description
Translesion Synthesis by POLH
HSF1 activation
ABC-family proteins mediated transport
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Hedgehog ligand biogenesis
Ovarian tumor domain proteases
Neutrophil degranulation
Protein methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Lin28atm1.1Gqda/Lin28atm1.1Gqda
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Lin28atm1.1Gqda/Lin28atm1.1Gqda
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0000418 patchy hair "uneven spots of hair growth on the body" [J:26975]
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Allelic Composition: Lin28atm1.1Gqda/Lin28atm1.1Gqda
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0000747 muscle weakness "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0000748 progressive muscle weakness "increasing loss of strength over time" [MGI:CLS, J:67994]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0000751 myopathy "any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0000759 abnormal skeletal muscle morphology "anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Lin28atm1.1Gqda/Lin28atm1.1Gqda
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0000938 motor neuron degeneration "retrogressive impairment of function or destruction of the cells that innervate an effector (muscle or glandular) tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Lin28atm1.1Gqda/Lin28atm1.1Gqda
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Lin28atm1.1Gqda/Lin28atm1.1Gqda
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Lin28atm1.1Gqda/Lin28atm1.1Gqda
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0002115 abnormal skeleton extremities morphology "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lin28atm1.1Gqda/Lin28atm1.1Gqda
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
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Allelic Composition: Lin28atm1.1Gqda/Lin28atm1.1Gqda
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB

 MP:0002183 gliosis "increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0002882 abnormal neuron "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0003084 abnormal skeletal muscle fiber morphology "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0003997 tonic-clonic seizures "increased number or decreased threshold for the induction of a seizure characterized by initial rigidity followed by rhythmic jerking movements" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0004016 decreased bone mass "a reduction in the total amount of bone tissue contained in the skeleton" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0004090 abnormal sarcomere morphology "any structural abnormality in the segment of a myofibril between two Z lines comprised of multi-protein complexes composed of three different filament systems; these systems work together to contract and relax muscle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0004148 increased cortical bone thickness "thicker than normal superficial layer of compact bone" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0004819 decreased skeletal muscle mass "reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0004984 increased osteoclast cell number "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0006038 increased mitochondrial proliferation "greater than normal reproduction of mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0008260 abnormal autophagy "abnormal catabolic process involving the degradation of a cell s own components through the lysosomal machinery" [MGI:honda "Hiraoki Onda, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0008396 abnormal osteoclast differentiation "atypical production of or inability to produce bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0009403 increased variability of skeletal muscle fiber size "greater range or dispersion within a distribution of skeletal muscle fiber size within a muscle compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0009404 centrally nucleated skeletal muscle fibers "cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0009414 skeletal muscle fiber necrosis "pathological cell death in the skeletal muscle fibers, usually due to irreversible damage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0009420 skeletal muscle endomysial fibrosis "replacement of the layer of connective tissue that ensheaths a muscle fiber by fibrous tissue resulting in separation of individual fibers" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0010933 decreased trabecular bone connectivity density "reduction in the extent of attachments between trabeculae; it may be expressed in ratios of nodes to free ends, trabecular bone pattern factor, and related measures" [ISBN:0120986523 "Principles of bone biology, Volume 1, Bilezikian, JP et al, eds"]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Pax3-cre)1Joe/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * NMRI * SJL

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
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Allelic Composition: Cd72tm1Jrp/Cd72tm1Jrp,Tg(BCL2)22Wehi/0
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6JWehi * SJL/JWehi) or (involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JWehi * SJL/JWehi)

Allelic Composition: Vcptm1.1Dts/Vcptm1.1Dts
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6 * FVB/N) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1 * FVB/N)

Allelic Composition: Vcptm1Dts/Vcptm1Dts
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

 MP:0011635 abnormal mitochondrial crista morphology "Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found; the shape can vary with the respiratory state of the mitochondria" [GO:0030061]
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Allelic Composition: Vcptm1Itl/Vcptm1Itl
Genetic Background: involves: 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000000751 Rpa1 / Q8VEE4 / Replication protein A 70 kDa DNA-binding subunit / P27694* / replication protein A1*  / reaction / complex
 ENSMUSG00000002633 Shh / Q62226 / Sonic hedgehog protein Sonic hedgehog protein N-product / Q15465* / sonic hedgehog*  / complex / reaction
 ENSMUSG00000012483 Rpa3 / Q9CQ71 / Replication protein A 14 kDa subunit / P35244* / replication protein A3*  / complex / reaction
 ENSMUSG00000023953 Polh / Q9JJN0 / DNA polymerase eta / Q9Y253*  / complex / reaction
 ENSMUSG00000024807 Syvn1 / synovial apoptosis inhibitor 1, synoviolin / Q86TM6* / synoviolin 1*  / complex
 ENSMUSG00000039703 Nploc4 / P60670 / Nuclear protein localization / Q8TAT6* / NPL4 homolog, ubiquitin recognition factor*  / complex
 ENSMUSG00000031986 Sprtn / G3X912 / SprT-like domain-containing protein Spartan / Q9H040* / SprT-like N-terminal domain*  / complex / reaction
 ENSMUSG00000031161 Hdac6 / Q9Z2V5 / Histone deacetylase 6 / Q9UBN7*  / complex
 ENSMUSG00000020311 Erlec1 / Q8VEH8 / Endoplasmic reticulum lectin 1 / Q96DZ1*  / complex / reaction
 ENSMUSG00000028452 Vcp / Q01853 / valosin containing protein / P55072*  / complex
 ENSMUSG00000040462 Os9 / Q8K2C7 / Protein OS-9 / Q13438* / OS9, endoplasmic reticulum lectin*  / complex / reaction
 ENSMUSG00000046404 Yod1 / Q8CB27 / YOD1 deubiquitinase / Q5VVQ6*  / complex / reaction
 ENSMUSG00000020964 Sel1l / Q9Z2G6 / sel-1 suppressor of lin-12-like (C. elegans) / Q9UBV2* / SEL1L ERAD E3 ligase adaptor subunit*  / complex
 ENSMUSG00000005262 Ufd1 / P70362 / ubiquitin recognition factor in ER-associated degradation 1 / Q92890*  / complex
 ENSMUSG00000028884 Rpa2 / replication protein A2 / P15927*  / complex / reaction
 ENSMUSG00000018442 Derl2 / Q8BNI4 / Derlin-2 / Q9GZP9*  / complex
 ENSMUSG00000027342 Pcna / P17918 / proliferating cell nuclear antigen / P12004*  / complex / reaction
 ENSMUSG00000049882 Q8C436 / Vcpkmt / valosin containing protein lysine (K) methyltransferase / Q9H867* / valosin containing protein lysine methyltransferase*  / reaction






 

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