ENSMUSG00000040462


Mus musculus

Features
Gene ID: ENSMUSG00000040462
  
Biological name :Os9
  
Synonyms : Os9 / Protein OS-9 / Q8K2C7
  
Possible biological names infered from orthology : OS9, endoplasmic reticulum lectin / Q13438
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 127095650
Gene end: 127121131
  
Corresponding Affymetrix probe sets: 10373036 (MoGene1.0st)   1426974_at (Mouse Genome 430 2.0 Array)   1426975_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079770
Ensembl peptide - ENSMUSP00000128914
Ensembl peptide - ENSMUSP00000151466
NCBI entrez gene - 216440     See in Manteia.
MGI - MGI:1924301
RefSeq - XM_011243420
RefSeq - NM_001171026
RefSeq - NM_177614
RefSeq Peptide - NP_001164497
RefSeq Peptide - NP_808282
swissprot - Q8K2C7
swissprot - A0A1W2P6Z8
Ensembl - ENSMUSG00000040462
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 os9ENSDARG00000020301Danio rerio
 OS9ENSG00000135506Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Erlec1 / Q8VEH8 / Endoplasmic reticulum lectin 1 / Q96DZ1*ENSMUSG0000002031116


Protein motifs (from Interpro)
Interpro ID Name
 IPR009011  Mannose-6-phosphate receptor binding domain superfamily
 IPR012913  Protein OS9-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006605 protein targeting IEA
 biological_processGO:0006621 protein retention in ER lumen IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0030970 retrograde protein transport, ER to cytosol IBA
 biological_processGO:0034976 response to endoplasmic reticulum stress IEA
 biological_processGO:1904153 negative regulation of retrograde protein transport, ER to cytosol IEA
 cellular_componentGO:0000836 Hrd1p ubiquitin ligase complex IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005788 endoplasmic reticulum lumen IBA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0005515 protein binding ISS
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
Hedgehog ligand biogenesis
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003036 vertebral transformation "homeotic transformation of a specific vertebrae to adopt the fate of another" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

 MP:0004609 vertebral fusion "the union of one or more vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002633 Shh / Q62226 / Sonic hedgehog protein Sonic hedgehog protein N-product / Q15465* / sonic hedgehog*  / complex / reaction
 ENSMUSG00000018442 Derl2 / Q8BNI4 / Derlin-2 / Q9GZP9*  / complex / reaction
 ENSMUSG00000020964 Sel1l / Q9Z2G6 / sel-1 suppressor of lin-12-like (C. elegans) / Q9UBV2* / SEL1L ERAD E3 ligase adaptor subunit*  / complex / reaction
 ENSMUSG00000024807 Syvn1 / synovial apoptosis inhibitor 1, synoviolin / Q86TM6* / synoviolin 1*  / complex / reaction
 ENSMUSG00000028452 Vcp / Q01853 / valosin containing protein / P55072*  / complex / reaction






 

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